An analysis of chronic kidney disease risk factors in a Louisiana nursing home population: a cross-sectional study.
An analysis of chronic kidney disease risk factors in a Louisiana nursing home population: a cross-sectional study.
复制标题
路易斯安那州疗养院人群慢性肾病危险因素的分析：一项横断面研究。
DOI：
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复制
发表时间：
2013
期刊：
影响因子：
--
通讯作者：
C. Cefalu
中科院分区：
文献类型：
--
作者：
Erwin A. Aguilar;H. Ashraf;M. Frontini;M. Ruiz;Tom Reske;C. Cefalu
背景
BACKGROUND
Chronic Kidney Disease (CKD) and its progression are associated with multiple risk factors. CKD is prevalent in nursing homes residents, but factors related to CKD in this setting have not been defined.
METHODS
A cross-sectional study was conducted (n=103). Data was abstracted using standardized forms and analyzed (SAS 9.2). Chi square and t-test statistics were used to compare proportions and means; correlation coefficients were used to describe associations. Logistic models were fit to the data to determine multivariate associations. Modification of Diet in Renal Disease (MDRD) formula was used to estimate GFR. CKD was defined according to established standards. A cutoff point of 60 was chosen for further analysis.
RESULTS
Twenty-three percent of subjects had CKD. Mean age for eGFR <60 was 70.8 +/- 13 and for eGFR >60 was 61.7 +/-14. Frequent co-morbidities were hypertension (75%), GERD (40%), obesity (39%), dyslipidemia (35%), depression (34%), anemia (32%), and diabetes (32%).
CONCLUSIONS
Our population is unique in terms of its age and reasons for nursing home admission. Factors associated with CKD in our study include age >65 years old, being male, having a positive history of cardiovascular disease (including congestive heart failure and coronary artery disease,) anemia, polypharmacy, and being obese (BMI >30). Further analysis showed that age and anemia are the strongest factors associated with CKD in our population. Management targeted at CKD risk factor reduction may play a vital role in controlling the magnitude of this disease. Prospective studies to investigate the relationship between gender, a BMI greater than 30, cardiovascular disease, and CKD and its complications are warranted.
影响因子：
13.2
作者：
Coresh, J;Astor, BC;Levey, AS
通讯作者：
Levey, AS
DOI：
10.2215/cjn.06770711
发表时间：
2011-12-01
影响因子：
9.8
作者：
Bowling, C. Barrett;Inker, Lesley A.;Muntner, Paul
通讯作者：
Muntner, Paul
DOI：
10.1053/j.ajkd.2009.09.035
发表时间：
2010-03
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
Stevens LA;Li S;Wang C;Huang C;Becker BN;Bomback AS;Brown WW;Burrows NR;Jurkovitz CT;McFarlane SI;Norris KC;Shlipak M;Whaley-Connell AT;Chen SC;Bakris GL;McCullough PA
通讯作者：
McCullough PA