STRUCTURE AND CYTOPATHIC EFFECTS OF NELSON BAY VIRUS
STRUCTURE AND CYTOPATHIC EFFECTS OF NELSON BAY VIRUS
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DOI：
10.1128/jvi.6.1.100-106.1970
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发表时间：
1970-01-01
影响因子：
5.4
通讯作者：
COMPANS, RW
中科院分区：
文献类型：
--
作者：
GARD, G;COMPANS, RW
从飞狐（脊髓灰质炎翼狐）中分离出的病毒具有与呼肠孤病毒相似的形态。然而，与呼肠孤病毒不同，该病毒具有快速的细胞病变作用，引起细胞融合、细胞质空泡化和不寻常的核变性。免疫荧光显示病毒抗原分布在细胞核和细胞质中。病毒成熟似乎发生在离散的细胞质工厂中，纺锤体小管没有明显的参与。
A virus isolated from a flying fox (Pteropus poliocephalus) has a morphology similar to that of reoviruses. However, unlike the reoviruses, this virus has a rapid cytopathic effect, causing cell fusion, vacuolization of the cytoplasm, and an unusual nuclear degeneration. Immunofluorescence indicates that viral antigen is distributed through both nucleus and cytoplasm. Viral maturation appears to take place in discrete cytoplasmic factories, and there is no apparent involvement of spindle tubules.