Mutations of the human beta 2-adrenergic receptor that impair coupling to Gs interfere with receptor down-regulation but not sequestration.
Mutations of the human beta 2-adrenergic receptor that impair coupling to Gs interfere with receptor down-regulation but not sequestration.
复制标题
人 β2-肾上腺素能受体的突变会损害与 G 的偶联,从而干扰受体下调,但不会干扰受体隔离。
作者:
Campbell,PT;Hnatowich,M;O'Dowd,BF;Caron,MG;Lefkowitz,RJ;Hausdorff,WP