Six Developmental Trajectories Characterize Children With Autism
Six Developmental Trajectories Characterize Children With Autism
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DOI：
10.1542/peds.2011-1601
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发表时间：
2012-05-01
期刊：
影响因子：
8
通讯作者：
Bearman, Peter S.
中科院分区：
文献类型：
--
作者：
Fountain, Christine;Winter, Alix S.;Bearman, Peter S.
关于这个主题的了解：自闭症被广泛认为是一种病因和表型上的异质性疾病。虽然自闭症通常是一种终身障碍，但人们对儿童在沟通和社会功能方面发展的速度或时间知之甚少。本研究补充：利用对大量自闭症儿童的年度评估，我们描述了从诊断到14岁的6个最常见的轨迹。轨迹显示出相当大的差异，高社会经济地位的儿童更有可能经历快速的改善。
WHAT'S KNOWN ON THIS SUBJECT: Autism is widely considered a heterogeneous disorder in terms of etiology and phenotype. Although autism is usually a lifelong disorder, little is known about the rate or timing of how children develop regarding their communication and social functioning.WHAT THIS STUDY ADDS: Utilizing annual evaluations for a large population of children with autism, we describe the 6 most common trajectories from diagnosis through age 14 years. Trajectories revealed considerable variation, and high socioeconomic status children were more likely to experience rapid improvement.