Vascular and structural alterations of the choroid evaluated by optical coherence tomography angiography and optical coherence tomography after half-fluence photodynamic therapy in chronic central serous chorioretinopathy
Vascular and structural alterations of the choroid evaluated by optical coherence tomography angiography and optical coherence tomography after half-fluence photodynamic therapy in chronic central serous chorioretinopathy
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DOI：
10.1007/s00417-018-04226-6
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发表时间：
2019-05-01
影响因子：
2.7
通讯作者：
Ozmert, Emin
中科院分区：
文献类型：
--
作者：
Demirel, Sibel;Ozcan, Gokcen;Ozmert, Emin
目的探讨半通量光动力疗法（hf PDT）对慢性中心性浆液性脉络膜视网膜病变（CSC）患者脉络膜毛细血管（CC）灌注及脉络膜结构的影响。分析增强深度成像光学相干断层扫描和光学相干断层血管造影（OCTA）图像。结果hf-PDT治疗后1个月，脉络膜总面积（CA）由1.490mm（2）降至1.312mm（2）（P
Purpose To concurrently evaluate the effect of half-fluence photodynamic therapy (hf PDT) on choriocapillaris (CC) perfusion and choroidal structure in chronic central serous chorioretinopathy (CSC).Methods This prospective study included 48 eyes of 41 patients with chronic CSC. Enhanced depth imaging optical coherence tomography and optical coherence tomography angiography (OCTA) images were analyzed. Choroidal area (CA), luminal area (LA), and stromal area (SA) were computed using Image J software.Results One month after hf-PDT, total CA decreased to 1.312mm(2) from 1.490mm(2) (p