PRESYNAPTIC INHIBITION IN CUNEATE NUCLEUS

PRESYNAPTIC INHIBITION IN CUNEATE NUCLEUS
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DOI:
10.1038/194741a0
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发表时间:
1962-01-01
期刊:
影响因子:
64.8
通讯作者:
ECCLES, JC
ECCLES, JC
中科院分区:
综合性期刊1区
文献类型:
--
作者:
ANDERSEN, P;SCHMIDT, RF;ECCLES, JC

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Fig. 1. A、B是由玻璃微电极从楔状核表面引出的电位,并由浅桡神经(SR)中的单次齐射和对侧感觉运动皮层(CORT”)的重复刺激诱发,而C、D是微电极尖端在1-1 mm的深度处。电位和时间尺度是针对AD,在楔背核(CUN NUC)及其环境的图(E)中,SR和CORT产生的P波的大小如文中所述,零响应用符号表示。CIDR是第一颈椎背根。F给出了楔状核中突触前末梢兴奋性的时间进程,这些兴奋性是用已经描述过的对照兴奋性的百分比来测量的(参考文献8),并在第一次条件刺激后对时间作图。G是从楔束和神经核C1的矢状面上画出的,显示了第一颈根。SR纤维的兴奋性变化在垂直箭头所示的三个位置处如F中那样进行测试,并且在51毫秒的测试间隔处显示增加。对于CORT”和45毫秒。对于M
Fig. 1. A, B are potentials led by a glass microelectrode from the surface of the cuneate nucleus and evoked by a single volley in the superficial radial nerve (SR) and by repetitive stimulation of the contralateral sensori-motor cortex (CORT"), while with C, D the microelectrode tip was at a depth of 1-1 mm. Potential and time-scales are for AD, In a drawing (E) of the dorsum of the cuneate nucleus (CUN NUC) and its environment, the sizes of the P waves produced by SR and CORT" are shown as described in the text, zero responses being shown by–signs. CIDR is first cervical dorsal root. F gives time courses of the excitabilities of presynaptic terminals in the cuneate nucleus which were measured as percentages of the control excitability as already described (ref. 8), and plotted against time after the first con-ditioning stimulus. G is drawn from a sagittal section of the cuneate tract and nucleus, C1, showing first cervical root. Excit-ability changes of the SR fibres were tested as in F at the three sites indicated by the vertical arrows, and the increases are shown at a testing interval of 51 msec. for CORT" and 45 msec. for M