Tailored excitation using nonlinear B0-shims.
Tailored excitation using nonlinear B0-shims.
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DOI:
10.1002/mrm.23278
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发表时间:
2012-03
影响因子:
3.3
通讯作者:
Duyn, Jeff
中科院分区:
文献类型:
--
作者:
Duan, Qi;van Gelderen, Peter;Duyn, Jeff
In high field MRI, RF flip angle inhomogeneity due to wavelength effects can lead to spatial variations in contrast and sensitivity. Improved flip angle homogeneity can be achieved through multi-dimensional excitation, but long RF pulse durations limit practical application. A recent approach to reduce RF pulse duration is based on parallel excitation through multiple RF channels. Here, an alternative approach to shorten multi-dimensional excitation is proposed that makes use of non-linear spatial variations in the stationary (B0) magnetic field during a B0-sensitive excitation pulse. As initial demonstration, the method was applied to 2D gradient echo (GE) MRI of human brain at 7T. Using B0 shims with up to second order spatial dependence, it is demonstrated that root-mean-squared flip angle variation can be reduced from 20% to 11% with RF pulse lengths that are practical for general GE imaging applications without requiring parallel excitation. The method is expected to improve contrast and sensitivity in GE MRI of human brain at high field.
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