ANTIFREEZE PEPTIDES CONFER FREEZING RESISTANCE TO FISH
ANTIFREEZE PEPTIDES CONFER FREEZING RESISTANCE TO FISH
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DOI：
10.1139/z86-284
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发表时间：
1986-09-01
影响因子：
1.4
通讯作者：
FOURNEY, RM
中科院分区：
文献类型：
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作者：
FLETCHER, GL;KAO, MH;FOURNEY, RM
人们普遍认为，血浆抗冻蛋白直接影响许多海洋硬骨鱼在充满冰的海水中生存的能力。然而，似乎没有直接的实验证据表明这一假设是正确的。在本研究中，冬鲽鱼（Pseudopleurectes americanus）表现出抗冻性的季节性变化，其数量与血浆抗冻蛋白水平的季节性变化相同。此外，当将冬鲽鱼抗冻蛋白注射到虹鳟鱼（Salmo gairdneri）（一种通常不具有抗冻蛋白的物种）中时，虹鳟鱼的抗冻能力与达到的血浆抗冻蛋白水平成正比。这些研究表明，抗冻蛋白直接影响许多海洋硬骨鱼在低于其血液的依数冰点的冰冷海水中生存的能力。鱼类似乎不需要特定物种的抗冻蛋白受体即可发挥作用。
It has been widely accepted that plasma antifreeze proteins are directly responsible for the ability of many marine teleosts to survive an ice-laden seawater. However, there appears to be no direct experimental evidence to indicate that this assumption is correct. In the present study winter flounder (Pseudopleuronectes americanus) showed seasonal changes in freezing resistance that were quantitatively the same as the seasonal changes in plasma antifreeze protein levels. Moreover, when winter flounder antifreeze proteins were injected into rainbow trout (Salmo gairdneri) (a species that does not normally possess antifreeze proteins) they increased the freezing resistance of the trout in direct proportion to plasma antifreeze protein levels attained. These studies indicate that antifreeze proteins are directly responsible for the ability of many marine teleosts to survive icy seawater at temperatures below the colligative freezing points of their blood. There appears to be no requirement for species-specific antifreeze protein receptors in the fish in order for them to act.