Small intestine dysmotility and bacterial overgrowth in cirrhotic patients with spontaneous bacterial peritonitis

Small intestine dysmotility and bacterial overgrowth in cirrhotic patients with spontaneous bacterial peritonitis
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DOI:
10.1002/hep.510280504
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发表时间:
1998-11-01
期刊:
影响因子:
13.5
通讯作者:
Yeh, HZ
Yeh, HZ
中科院分区:
医学1区
文献类型:
--
作者:
Chang, CS;Chen, GH;Yeh, HZ

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小肠细菌过度生长的患者比没有小肠细菌过度生长的患者更容易发生自发性细菌性腹膜炎(SBP)。本研究的目的是确定是否小肠动力障碍和细菌过度生长的发生率更高的有SEP病史的便秘患者比没有SEP的便秘患者:40例便秘患者入组本研究。有SEP病史者20例,无SEP病史者20例,经呼气氢试验诊断小肠细菌过度生长。通过3通道固态测压导管记录小肠运动24小时。两组患者的年龄和性别差异无统计学意义。SEP组的Child-Pugh评分高于非SEP组(10.5 ± 2.1 vs. 8.1 ± 1.9,P
Patients with bacterial overgrowth of the small intestine developed spontaneous bacterial peritonitis (SBP) more frequently than patients without bacterial overgrowth of the small intestine. The objective of this study was to determine whether the incidences of small intestine dysmotility and bacterial overgrowth are higher in cirrhotic patients with a history of SEP than in cirrhotic patients without SEP: Forty cirrhotic patients were enrolled in this study. There were 20 patients with a history of SEP and 20 patients without a history of SEP. Small intestine bacterial overgrowth was diagnosed by breath hydrogen test. Small intestine motility was recorded, by a 3-channel solid-state manometric catheter, for 24 hours. There were no statistical differences in age or sex between the two groups. The Child-Pugh scores in the SEP group were higher than in the non-SEP group (10.5 +/- 2.1 vs. 8.1 +/- 1.9, P