Formation of the Gel Layer of Polymers and Its Effect on the Permeation Flux in Crossflow Filtration of Corynebacterium glutamicum Broth

Formation of the Gel Layer of Polymers and Its Effect on the Permeation Flux in Crossflow Filtration of Corynebacterium glutamicum Broth
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谷氨酸棒杆菌培养液错流过滤中聚合物凝胶层的形成及其对渗透通量的影响

DOI:
10.1080/01496399808544784
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发表时间:
1998
影响因子:
2.8
通讯作者:
K. Nakanishi
K. Nakanishi
中科院分区:
工程技术4区
文献类型:
--
作者:
Takaaki Tanaka;Kensuke Usui;K. Nakanishi

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ABSTRACT The behavior of the permeation flux in crossflow filtration of Corynebacterium glutamicum broth was studied. In the beginning of filtration the permeation flux changed in accordance with the cake filtration model. The permeation flux agreed with the value calculated from the weight of the cell layer formed on the membrane per unit filtration area and the specific resistance of the cell layer measured in dead-end filtration. After cell deposition on the membrane, permeation resistance rapidly increased. The increase was due to the formation of the gel layer of the proteins and polysaccharides in the supernatant of the broth. When the circulation flow rate was raised, the weight of the cell layer reduced. However, the beginning of the rapid increase of permeation resistance came earlier and the apparent specific resistance of the cell layer increased. The higher the circulation flow rate, the higher the permeation flux at the beginning of the rapid increase of resistance. When the transmembrane pre...
Takaaki TANAKA:“影响酵母细胞悬浮液错流过滤性能的因素”生物技术与生物工程。
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