Childhood Calcinosis Cutis
Childhood Calcinosis Cutis
复制标题
儿童皮肤钙质沉着症
DOI：
10.1111/j.1525-1470.1996.tb01415.x
复制
发表时间：
2010
影响因子：
1.5
通讯作者：
A. Castells
中科院分区：
文献类型：
--
作者：
L. Rodríguez‐Cano;V. García;Margaret Creus;P. Bastida;J. J. Ortega;A. Castells
摘要：皮肤钙质沉着症是一种罕见的疾病，其特征是磷酸钙的羟基磷灰石晶体沉积在皮肤上，在儿童时期很少被描述。传统上，它被分为营养不良型、转移性和特发性。我们报告一个8岁女孩，因肿瘤溶解综合征继发高磷血症，在先前的坏疽性脓胸病变上出现局部软组织钙化。静脉输注葡萄糖酸钙可能是诱发因素。我们的病例说明，皮肤钙质沉着症可能同时涉及几种病因致病机制。
Abstract: Calcinosis cutis, an uncommon disorder characterized by hydroxyapatite crystals of calcium phosphate deposited in the skin, has been described infrequently in childhood. Classically, it is divided into dystrophic, metastatic, and idiopathic types. We report an 8‐year‐old girl with hyperphosphatemia secondary to a tumor lysis syndrome, who developed a localized soft tissue calcification over a previous lesion of ec‐thyma gangrenosum. Intravenous infusion of calcium gluconate was probably the precipitating factor. Our case illustrates that several etio‐pathogenic mechanisms may be simultaneously involved in calcinosis cutis.