Long-term impact of transcatheter atrial septal defect closure in adults on cardiac function and exercise capacity

Long-term impact of transcatheter atrial septal defect closure in adults on cardiac function and exercise capacity
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DOI:
10.1016/j.ijcard.2006.12.031
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发表时间:
2008-02-29
影响因子:
3.5
通讯作者:
Picchio, Fernando M.
Picchio, Fernando M.
中科院分区:
医学2区
文献类型:
--
作者:
Giardini, Alessandro;Donti, Andrea;Picchio, Fernando M.

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背景资料:经导管房间隔缺损(ASD)封堵术对右心室(RV)重构和运动能力的长期影响尚不清楚。(年龄42.3 +/- 16.4岁),在经导管缺损封堵术前和封堵术后6个月和>36个月时,血流动力学显著ASD。与闭合后6个月相比,峰值摄氧量进一步改善(p
Background: The long-term impact of transcatheter atrial septal defect (ASD) closure on right ventricular (RV) remodeling and exercise capacity is unknown.Methods: We studied with cardiopulmonary exercise testing and transthoracic echocardiography 29 adults (age 42.3 +/- 16.4 years) with hemodynamically significant ASD just before transcatheter defect closure and after 6 and >36 months from closure.Results: Compared to 6 months after closure, a further improvement of peak oxygen uptake (p