Spreading of nonmotile bacteria on a hard agar plate: Comparison between agent-based and stochastic simulations.

Spreading of nonmotile bacteria on a hard agar plate: Comparison between agent-based and stochastic simulations.
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非运动细菌在硬琼脂平板上的传播:基于试剂的模拟和随机模拟之间的比较。

DOI:
10.1103/physreve.96.052403
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发表时间:
2017
期刊:
Physical review. E
影响因子:
--
通讯作者:
P. Perlekar
P. Perlekar
中科院分区:
--
文献类型:
--
作者:
Navdeep Rana;Pushpita Ghosh;P. Perlekar

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我们研究了一个非运动细菌菌落在硬琼脂板上的传播使用基于代理和连续体模型。我们表明,传播动态取决于初始营养浓度,流动性和固有的人口噪声。种群波动在基于主体的模型中是固有的,而对于连续体模型,我们使用随机朗格万方程对它们进行建模。研究表明,随着初始营养物质浓度的降低,内在种群波动与非线性扩散率的耦合导致了由扩散受限聚集型形态向伊甸园型形态的转变。
We study spreading of a nonmotile bacteria colony on a hard agar plate by using agent-based and continuum models. We show that the spreading dynamics depends on the initial nutrient concentration, the motility, and the inherent demographic noise. Population fluctuations are inherent in an agent-based model, whereas for the continuum model we model them by using a stochastic Langevin equation. We show that the intrinsic population fluctuations coupled with nonlinear diffusivity lead to a transition from a diffusion limited aggregation type of morphology to an Eden-like morphology on decreasing the initial nutrient concentration.
DOI: 10.1126/science.44.1129.244
发表时间: --
期刊: Science
影响因子: 56.9
作者:
V. Gates;.. M. L. Ludwig-M.-L.-Ludwig-2273875465;J. A. Hartsuck;T. A. Steitz;H. Muirhead;J. C. Coppola;G. N. Reeke
通讯作者: V. Gates;.. M. L. Ludwig-M.-L.-Ludwig-2273875465;J. A. Hartsuck;T. A. Steitz;H. Muirhead;J. C. Coppola;G. N. Reeke