Chemokines and leukocyte traffic
Chemokines and leukocyte traffic
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DOI：
10.1038/33340
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发表时间：
1998-04-09
期刊：
影响因子：
64.8
通讯作者：
Baggiolini, M
中科院分区：
文献类型：
--
作者：
Baggiolini, M
在过去的十年中，许多趋化因子已被确定为不同类型的血液白细胞到感染和炎症部位的引诱剂。它们在组织中局部产生，并通过选择性受体作用于白细胞。现在已知趋化因子也作为调节分子在白细胞成熟、淋巴细胞的运输和归巢以及淋巴组织的发育中起作用。
Over the past ten years, numerous chemokines have been identified as attractants of different types of blood leukocytes to sites of infection and inflammation. They are produced locally in the tissues and act on leukocytes through selective receptors. Chemokines are now known to also function as regulatory molecules in leukocyte maturation, traffic and homing of lymphocytes, and the development of lymphoid tissues.