Identification and production of flavonoids in a cell suspension culture of Scutellaria baicalensis G.
Identification and production of flavonoids in a cell suspension culture of Scutellaria baicalensis G.
复制标题
DOI：
10.1007/bf00234703
复制
发表时间：
1993-05
影响因子：
6.2
通讯作者：
W. Seo;Y. H. Park;T. Choe
中科院分区：
文献类型：
--
作者：
W. Seo;Y. H. Park;T. Choe
A high yielding cell line ofScutellaria baicalensisG. has successfully been developed to produce flavonoids. Major components of the flavonoids were identified as baicalin and wogonin-7-O-glucuronic acid by a series of instrumental analyses using UV, IR, MASS, and NMR. After 12 days in suspension culture, the cell growth reached 14gDW/l, and baicalin and wogonin-7-O-glucuronic acid were obtained in concentrations of 2.9g/land 1.07g/l, respectively. The culture temperature was found to be an important parameter for improving production yield of the flavonoids. The yield of baicalin was observed to increase to 4.2g/lby shifting the temperature from 30 °C to 25 °C after 72 h of suspension culture.
