A Neuro-Influence Experiment to Evaluate the Persuasiveness of Pre-Exposure Prophylaxis Promotion Messages Among Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial.
A Neuro-Influence Experiment to Evaluate the Persuasiveness of Pre-Exposure Prophylaxis Promotion Messages Among Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial.
复制标题
DOI：
10.2196/52546
复制
发表时间：
2023-12-06
影响因子：
1.7
通讯作者：
中科院分区：
文献类型：
--
作者：
暴露前预防（PrEP）是由美国疾病控制和预防中心推荐的，但行为因素限制了吸收，特别是在与男性发生性关系的男性中。更好地了解人类如何认知处理信息可以为健康信息的开发提供信息，以促进PrEP的吸收。本文是由神经科学的说服力和影响力，并描述了神经影响实验的协议，使用功能性近红外光谱（fNIRS），以评估的说服力的PrEP促进信息之间发生性关系的男性在巴尔的摩，马里兰州。我们将进行一项随机对照试验，使用fNIRS来测量60名参与者的大脑激活，这些参与者观看了通过研究团队实施的众包公开竞赛开发的PrEP促销信息，或使用传统的社会营销方法开发的PrEP促销信息。我们将通过评估与说服相关的大脑激活以及两组之间PrEP意愿、行为意图、发起和行动的变化来评估PrEP宣传信息的有效性。这项研究由美国国立卫生研究院（National Institute of Mental Health）资助（编号：R34MH116725）。参与者招募及数据收集已于2023年10月完成。第一批结果预计将于2024年提交出版。除了深入了解PrEP推广信息的有效性外，本研究还将研究神经影像学技术的可行性、可接受性和实用性，以评估高危男性的PrEP推广信息。这些发现还可以证明fNIRS作为健康活动产品前测试工具的实用性，并使公共卫生界能够提供更有效的信息以改善健康结果。DERR1-10.2196/52546
Pre-exposure prophylaxis (PrEP) is recommended by the US Centers for Disease Control and Prevention, but behavioral factors limit uptake, especially among men who have sex with men. A better understanding of how humans cognitively process information may inform health message development to promote PrEP uptake. This paper is informed by the neuroscience of persuasion and influence and describes the protocol of a neuro-influence experiment using functional near-infrared spectroscopy (fNIRS) to evaluate the persuasiveness of PrEP promotion messages among men who have sex with men in Baltimore, Maryland. We will conduct a randomized controlled trial using fNIRS to measure brain activation among 60 participants viewing PrEP promotion messages either developed through a crowdsourcing open contest implemented by the study team or developed with a traditional social marketing approach. We will evaluate the effectiveness of PrEP promotion messages by assessing brain activation in the regions associated with persuasion and changes in PrEP willingness, behavioral intention, initiation, and action between the 2 groups. This study is funded by the National Institutes of Health (National Institute of Mental Health: R34MH116725). Participant recruitment and data collection were completed in October 2023. The first results are expected to be submitted for publication in 2024. In addition to providing insight into the effectiveness of PrEP promotion messages, this study will examine the feasibility, acceptability, and utility of neuroimaging techniques to evaluate PrEP promotion messages for high-risk men who have sex with men. The findings can also demonstrate the utility of fNIRS as a tool for preproduct testing of health campaigns and enable the public health community to deliver more effective messages to improve health outcomes. DERR1-10.2196/52546