Abdominal obesity and the prevalence of diabetes and intermediate hyperglycaemia in Chinese adults
Abdominal obesity and the prevalence of diabetes and intermediate hyperglycaemia in Chinese adults
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DOI：
10.1017/s1368980008003856
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发表时间：
2009-08-01
影响因子：
3.2
通讯作者：
Yang, Xiaoguang
中科院分区：
文献类型：
--
作者：
He, Yuna;Zhai, Fengying;Yang, Xiaoguang
目的：评估中国人群中一般肥胖和腹部肥胖指标与2型糖尿病（T2DM）和中度高血糖（IHG）患病率的关系。方法：采用2002年全国营养与健康调查中50905名18 ~ 79岁成年人的资料。BMI （24 kg/m(2)）和腰围（WC，男性85 cm，女性80 cm）采用推荐的中国临界值。通过受试者工作特征（ROC）曲线分析，确定腰高比（WHtR）的最佳截止值。结果：T2DM和IHG患病率分别为2.6%和1.9%。ROC曲线分析显示，男女WHtR的最佳临界值为0.5。高BMI、WC和WHtR均与糖耐量异常患病率相关，高WHtR患病率最高（PR）（男性：PR = 2.85, 95% CI 2.54, 3.21；女性：PR = 3.10, 95% CI 2.74, 3.51）。当结合BMI和腰宽比时，在男性中，高BMI或高腰宽比单独与风险增加相关。在女性中，没有伴随高腰宽比的高BMI与糖耐量异常风险增加无关，而无论BMI如何，高腰宽比与风险相关。结论：在中国成年人中，中心性肥胖指标比BMI更能预测糖耐量异常的患病率。男性和女性的WHtR截断点均为0.5，可被认为是预测（前期）糖尿病的最佳值，可能是筛查和健康教育的有用工具。
Objective: To assess the association of indicators of general and abdominal obesity with the prevalence of type 2 diabetes (T2DM) and intermediate hyperglycaemia (IHG) in the Chinese population.Methods: We used data of 50905 adults aged 18-79 years in the 2002 China National Nutrition and Health Survey. Recommended Chinese cut-off values were used for BMI (24 kg/m(2)) and waist circumference (WC; 85 cm in men, 80 cm in women). Optimal cut-offs for waist:height ratio (WHtR) were determined from analyses of receiver-operating characteristic (ROC) curves.Results: The prevalence of T2DM and IHG was 2.6% and 1.9% respectively. ROC curve analyses indicated 0.5 as the optimal cut-off value for WHtR in both sexes. High BMI, WC and WHtR were all associated with the prevalence of glucose tolerance abnormalities, with the highest prevalence ratio (PR) for high WHtR (men: PR = 2.85, 95% CI 2.54, 3.21; women: PR = 3.10, 95% CI 2.74, 3.51). When combining BMI and WHtR, in men either a high BMI or a high WHtR alone was associated with increased risk. Among women, a high BMI without a concomitant high WHtR was not associated with increased glucose tolerance abnormalities risk, whereas a high WHtR was associated with risk irrespective of BMI.Conclusions: Among the Chinese adult population measures of central obesity are better predictors of glucose tolerance abnormalities prevalence than BMI. A WHtR cutoff point of 0.5 for both men and women can be considered as optimum for predicting (pre-) diabetes and may be a useful tool for screening and health education.