Predictors of fetal anemia and cord blood malaria parasitemia among newborns of HIV-positive mothers.
Predictors of fetal anemia and cord blood malaria parasitemia among newborns of HIV-positive mothers.
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DOI：
10.1186/1756-0500-6-350
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发表时间：
2013-09-03
影响因子：
1.8
通讯作者：
Quakyi, Isabella A
中科院分区：
文献类型：
--
作者：
Laar, Amos K;Grant, Fredrick E;Quakyi, Isabella A
背景：怀孕期间的疟疾和艾滋病毒感染可以单独或共同导致或混淆妊娠结局。其中两种可能的结果是胎儿贫血和脐带血疟原虫血症。我们确定了加纳两个地区 HIV 阳性妇女新生儿中与胎儿贫血和脐带血疟原虫血症相关的临床和人口因素。 结果：我们招募了 1,154 名产前参与者（443 名 HIV 阳性和 711 名 HIV 阴性），其中 66% 在分娩时进行了前瞻性随访。入组时 HIV+ 参与者的孕产妇疟原虫血症和贫血率分别为 20.3% 和 78.7%，HIV-参与者中的孕产妇疟原虫血症和贫血率分别为 12.8% 和 51.6%。使用多元线性和逻辑回归模型来研究关联性。胎儿贫血的患病率（脐带血红蛋白水平
BACKGROUND: Malaria and HIV infections during pregnancy can individually or jointly unleash or confound pregnancy outcomes. Two of the probable outcomes are fetal anemia and cord blood malaria parasitemia. We determined clinical and demographic factors associated with fetal anemia and cord blood malaria parasitemia in newborns of HIV-positive women from two districts in Ghana.RESULTS: We enrolled 1,154 antenatal attendees (443 HIV-positive and 711 HIV-negative) of which 66% were prospectively followed up at delivery. Maternal malaria parasitemia, and anemia rates among HIV+ participants at enrolment were 20.3% and 78.7% respectively, and 12.8% and 51.6% among HIV- participants. Multivariate linear and logistic regression models were used to study associations. Prevalence of fetal anemia (cord hemoglobin level