Pubertal maturation in girls and the relationship to anthropometric changes: Pathways through puberty
Pubertal maturation in girls and the relationship to anthropometric changes: Pathways through puberty
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DOI：
10.1067/mpd.2003.244
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发表时间：
2003-06-01
影响因子：
5.1
通讯作者：
Morrison, JA
中科院分区：
文献类型：
--
作者：
Biro, FM;Lucky, AW;Morrison, JA
目的青春期成熟的模式可能会影响与成人发病率和死亡率相关的几个危险因素，如肥胖。我们研究了青春期的女孩与人体测量的措施，以及初潮年龄的初步表现的关系。方法白色女性（n = 1166，9岁和10岁的摄入量）进行了为期10年的年度访问。体格检查包括身高，体重，皮褶厚度，和青春期成熟assessment.Results在研究过程中，443 859名合格的女性（51.6%）被观察到有异步成熟的青春期发育，即最初乳晕/乳房（thelarche途径）或阴毛（adrenarche途径）的发展，没有发展的其他特征。使用纵向回归模型，注意到青春期初始表现和青春期开始后的年数之间在以下结果上的显著相互作用：皮褶厚度之和、体脂百分比、腰臀比和体重指数（BMI）。然而，青春期成熟的开始年龄是相同的组（10.7岁）。乳房初潮途径中的女性初潮较早（12.6 vs 13.1岁），初潮时的皮褶、体脂和BMI也较大。女性在thelarche途径也有更大的身体脂肪和体重指数1年前青春期和整个青春期相比，在adrenarche pathway.Conclusions女性谁进入青春期通过thelarche途径，相比adrenarche途径，有更大的总和皮褶厚度，体重指数和体脂百分比1年前发病，以及整个青春期。由于乳房初潮途径中女性较大的身体组成和较早的初潮年龄与肥胖或有肥胖风险的女性的流行病学特征平行，因此这些女性可能有更大的成年肥胖风险。
Objective Patterns of pubertal maturation may have an impact on several risk factors associated with adult morbidity and mortality, such as obesity. We examined the relationship of the initial manifestation of puberty in girls with anthropometric measures, as well as age at menarche.Methods White females (n = 1166, ages 9 and 10 at intake) were followed with annual visits for 10 years. Physical examinations included height, weight, skinfold thicknesses, and pubertal maturation assessment.Results During the course of the study, 443 of 859 eligible females (51.6%) were observed to have asynchronous maturation in the development of puberty, that is, initial areolar/breast (thelarche pathway) or pubic hair (adrenarche pathway) development, without development of the other characteristic. Using a longitudinal regression model, significant interactions were noted between initial pubertal manifestation and years since onset of puberty on the following outcomes: sum of skinfolds thickness, percent body fat, waist-to-hip ratio, and body mass index (BMI). However, age of onset of pubertal maturation was the same in the groups (10.7 years). Females in the thelarche pathway had earlier menarche (12.6 vs 13.1 years) as well as greater skinfolds, body fat, and BMI at the time of menarche. Females in the thelarche pathway also had greater body fat and BMI 1 year before puberty and throughout puberty compared with those in the adrenarche pathway.Conclusions Females who enter puberty through the thelarche pathway, as compared with the adrenarche pathway, had greater sum of skinfold thicknesses, BMI, and percent body fat 1 year before the onset, as well as throughout, puberty. Because larger body composition and earlier age of menarche of females in the thelarche pathway parallel the epidemiologic profiles of women who are obese or at risk for obesity, these females may be at greater risk for adult obesity.