Short range ballistic motion in fluid lipid bilayers studied by quasi-elastic neutron scattering
Short range ballistic motion in fluid lipid bilayers studied by quasi-elastic neutron scattering
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DOI：
10.1039/c1sm05691c
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发表时间：
2011-01-01
期刊：
影响因子：
3.4
通讯作者：
Rheinstaedter, M. C.
中科院分区：
文献类型：
--
作者：
Armstrong, C. L.;Trapp, M.;Rheinstaedter, M. C.
扩散是脂质和蛋白质在生物膜的横向方向上移动的主要机制。本文利用准弹性中子散射研究了脂质分子在DMPC流体膜中的扩散过程。我们发现，在大于脂质直径的长度尺度上的运动可以被表征为连续扩散过程，扩散系数为D = 64 × 10（-12）m（2）/s。连续扩散模型在过去已经成功地用于描述长尺度上的脂质运动。然而，这种测量的重点是确定分子运动的特征如何在短于最近邻距离的长度尺度上变化。在非常短的长度尺度上（
Diffusion is the primary mechanism for movement of lipids and proteins in the lateral direction of a biological membrane. In this paper we have used quasi-elastic neutron scattering to examine the diffusion process of lipid molecules in fluid DMPC membranes. We found that the motion over length scales greater than the lipid diameter could be characterized as a continuous diffusion process, with a diffusion coefficient of D = 64 x 10(-12) m(2)/s. The continuous diffusion model has been successfully used in the past to describe the motion of lipid over long length scales. However, the focus of this measurement was to determine how the character of the molecular motion changes on length scales shorter than the nearest neighbour distance. At very short length scales (