Spontaneous progression of peri-implantitis at different types of implants. An experimental study in dogs. I: clinical and radiographic observations
Spontaneous progression of peri-implantitis at different types of implants. An experimental study in dogs. I: clinical and radiographic observations
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DOI：
10.1111/j.1600-0501.2008.01589.x
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发表时间：
2008-10-01
影响因子：
4.3
通讯作者：
Berglundh, Tord
中科院分区：
文献类型：
--
作者：
Albouy, Jean-Pierre;Abrahamsson, Ingemar;Berglundh, Tord
目的：本研究的目的是分析在实验性种植体周围暴露的商用种植体去除结扎后斑块形成的组织反应。材料和方法：使用6只1岁左右的拉布拉多犬。拔除所有下颌前磨牙和上颌两侧的3颗前磨牙。3个月后，分别代表4种不同表面特征的种植体系统--种植体A组(车削)、种植体B组(TiOblast)、种植体C组(喷砂酸蚀；SLA)和种植体D(TiUnite)-按随机顺序放置在下颌骨的右侧。种植体植入三个月后，通过在边缘下放置结扎线和斑块堆积来启动实验性种植体周围炎。在12周时，当大约40%-50%的支持骨丢失时，结扎被移除。在随后的24周期间，斑块继续堆积。在“活动性破坏”期间(斑块积聚和结扎)和解除结扎后的斑块积累期进行放射学和临床检查。实验在36周结束。结果：在“活动崩溃”期间发生的骨丢失在3.5 mm到4.6 mm之间。在去除结扎后的菌斑聚集期内发生的额外骨丢失分别为1.84(A)、1.72(B)、1.55(C)和2.78 mm(D)。结论：不同几何形状和表面特征的种植体可诱发种植体周围炎症的自发进展。进展在D型种植体(TiUnite表面)最为明显。
Aim: The aim of the present study was to analyze tissue reactions to plaque formation following ligature removal at commercially available implants exposed to experimental peri-implantitis.Material and methods: Six Labrador dogs about 1 year old were used. All mandibular premolars and the three anterior premolars in both sides of the maxilla were extracted. After 3 months four implants representing four different implant systems with different surface characteristics - implant group A (turned), B (TiOblast), C (sandblasted acid-etched; SLA) and D (TiUnite) - were placed in a randomized order in the right side of the mandible. Three months after implant installation experimental peri-implantitis was initiated by placement of ligatures in a submarginal position and plaque accumulation. At week 12, when about 40-50% of the supporting bone was lost, the ligatures were removed. During the subsequent 24-week period plaque accumulation continued. Radiographic and clinical examinations were performed during the 'active breakdown' period (plaque accumulation and ligatures) and the plaque accumulation period after ligature removal. The experiment was terminated at week 36.Results: The bone loss that took place during the 'active breakdown' period varied between 3.5 and 4.6 mm. The additional bone loss that occurred during the plaque accumulation period after ligature removal was 1.84 (A), 1.72 (B), 1.55 (C) and 2.78 mm (D).Conclusion: Spontaneous progression of experimentally induced peri-implantitis occurred at implants with different geometry and surface characteristics. Progression was most pronounced at implants of type D (TiUnite surface).