Prevalence of vancomycin-resistant enterococcus in Africa in one health approach: a systematic review and meta-analysis.
Prevalence of vancomycin-resistant enterococcus in Africa in one health approach: a systematic review and meta-analysis.
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DOI：
10.1038/s41598-020-77696-6
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发表时间：
2020-11-25
影响因子：
4.6
通讯作者：
Hailemariam M
中科院分区：
文献类型：
--
作者：
Alemayehu T;Hailemariam M
据世界卫生组织报道，对万古霉素耐药的肠球菌是目前面临的全球性挑战。还必须认识到，防治抗菌素耐药性需要认识到人、动物、植物及其共有环境在创造公共卫生方面的相互联系，即所谓的同一健康办法。虽然世界上许多地区都描述了VRE的存在，但缺乏全面的数据表明其在非洲的流行情况。因此，这项研究的目的是汇总描述非洲多个地区报告的VRE的研究结果。应用计算机检索2019年8月1-3日谷歌学者PubMed和Hinari的文献，检索词“非洲万古霉素耐药肠球菌”。所有可用的文章都被下载到“Endnote 7.1版”，然后下载到Microsoft Word 2013。被确定为符合我们的审查标准的文章被提取到Microsoft Excel 2013。从所有样本类型获得的报道万古霉素耐药肠球菌流行率的文章以英文发表，纳入审查范围。采用OpenMetaAnalyst R.3.1.0软件进行Meta分析。使用二进制随机效应模型确定效应大小，并在p <； 0.05时考虑静态显著。用不一致性指数判定非均质性。用于执行敏感度分析的留一分析。从数据库中检索到151篇文章；其中36篇文章是在与两名独立作者进行广泛审查后收录的。在收集的4073个样本中，从单一健康的角度来看，在非洲确认了1488个分离株，总体VRE合并患病率为26.8%(95%可信区间；10.7-43.0%)。分析表明，这些研究之间存在相当大的异质性(I2 = 99.97%；p <； 0.001)。国家、非洲地区、实验室方法、发表年份和样本来源的亚组分析表明，南非(74.8%)、南非地区(74.8%)、聚合酶链式反应(959.2%)、2010年至2015年(30.3%)和环境(52.2%)分别确定了高患病率。这一荟萃分析表明，在非洲对万古霉素耐药的肠球菌有很高的流行范围。要预防和控制耐万古霉素肠球菌从大陆环境向人的传播，需要做很多工作。
Vancomycin-resistant enterococci are a global challenge currently as reported by the World Health Organization. It is also important to recognize that combating antimicrobial resistance needs to recognize the interconnections between people, animals, plants and their shared environment in creating public health, the so-called One Health approach. Although the presence of VRE has been described in many regions of the world, there is a lack of comprehensive data indicating their prevalence of in Africa. Therefore, this study aimed to aggregate the result of studies describing VRE reported across multiple regions in Africa. A literature search was conducted on PubMed, Google scholar, and Hinari with the term “Vancomycin resistance enterococcus in Africa” on August 1–3, 2019. All available articles were downloaded to “Endnote version 7.1” then to Microsoft Word 2013. Articles determined to meet our criteria for the review was extracted to Microsoft Excel 2013. Those articles that reported the prevalence of vancomycin resistance Enterococcus obtained from all sample types and published from 2010 to 2019 in the English language were included for the review. A meta-analysis was conducted with OpenMetaAnalyst version R.3.1.0 software. The effect size was determined using a binary random effect model and statically significant considered when p < 0.05. Heterogeneity determined with the inconsistency index. A leave one out analysis used to perform the sensitivity analysis. There were 151 articles identified from the database searches; of this, 36 articles included after extensive review with two independent authors. Out of 4073 samples collected, 1488 isolates identified with an overall pooled prevalence of VRE 26.8% (95% CI; 10.7–43.0%) in Africa with a one-health perspective. The analysis showed that considerable heterogeneity among the studies (I2 = 99.97%; p < 0.001). Subgroup analysis in-country, African region, laboratory method, year of publication, and sample source showed that a high prevalence was identified from South Africa (74.8%), South African regions (74.8%), PCR (959.2%), 2010–2015 years (30.3%) and environmental (52.2%), respectively. This meta-analysis indicates that there was a high-pooled prevalence of vancomycin-resistant enterococci in African. A lot should be done to prevent and control the transmission of vancomycin resistance enterococci to a human being from the environment in the continent.
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DOI：
10.1590/s0037-86822011005000009
发表时间：
2011-04-01
影响因子：
2
作者：
Conceição, Natália;Oliveira, Cristina da Cunha Hueb Barata de;Oliveira, Adriana Gonçalves de
通讯作者：
Oliveira, Adriana Gonçalves de
影响因子：
4.2
作者：
Deschaght P;De Baere T;Van Simaey L;Van Daele S;De Baets F;De Vos D;Pirnay JP;Vaneechoutte M
通讯作者：
Vaneechoutte M
2014年，埃塞俄比亚西北部的贾比森南地区，五岁以下儿童急性腹泻的患病率和决定因素。
影响因子：
4.5
作者：
Anteneh ZA;Andargie K;Tarekegn M
通讯作者：
Tarekegn M
影响因子：
1.9
作者：
Bouamama, Lamiaa;Sorlozano, Antonio;Gutierrez, Jose
通讯作者：
Gutierrez, Jose
影响因子：
2
作者：
Bouymajane, Aziz;Rhazi Filali, Fouzia;Moumni, Mohieddine
通讯作者：
Moumni, Mohieddine