Patterns of diet-related practices and prevalence of gastro-esophageal reflux disease
Patterns of diet-related practices and prevalence of gastro-esophageal reflux disease
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DOI：
10.1111/nmo.12192
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发表时间：
2013-10-01
影响因子：
3.5
通讯作者：
Adibi, P.
中科院分区：
文献类型：
--
作者：
Esmaillzadeh, A.;Keshteli, A. H.;Adibi, P.
背景没有研究评估潜在类别分析（LCA）确定的饮食相关实践模式与胃食管反流病（GERD）之间的关联。我们的目的是评估这种关系在一个大样本的伊朗adultes.MethodsIn一项横断面研究中，在4763名成年人，饮食相关的做法进行了评估，在四个领域，膳食模式“，进食率”，餐内液体摄入量“，和吃饭到睡眠的时间间隔”，使用预先测试的问卷。LCA被应用于确定类饮食相关的做法。我们将GERD定义为胃灼热的存在有时，经常或always.Key ResultsThe GERD的患病率在研究人群中为23.5%（n=1120）。我们确定了两种不同的膳食模式：定期和不定期，三类进食率：中度，中度至缓慢，中度至快速，两个主要类别的液体摄入与膳食：中度和大量的餐内饮酒，两类关于吃饭和睡觉之间的间隔：短的“和长的吃饭到睡觉”的间隔。调整潜在混杂因素后，不规则膳食模式的受试者“与规则膳食模式的受试者相比，GERD的几率更高”（OR：1.21; 1.00-1.46）。然而，当考虑到BMI时，这种关联就消失了。与进餐至睡眠间隔较短相比，进餐至睡眠间隔较长与GERD呈负相关（OR：0.73; 95%CI：0.57-0.95）。进食率和餐内液体摄入量与GERD.Conclusions和InferencesOur数据表明饮食模式和GERD之间存在一定的关联。这些发现值得在前瞻性研究中进行评估，以确定饮食行为改变对GERD管理的潜在价值。
BackgroundNo studies have evaluated associations between patterns of diet-related practices as determined by latent class analysis (LCA) and gastro-esophageal reflux disease (GERD). We aimed to assess this relationship in a large sample of Iranian adults.MethodsIn a cross-sectional study in 4763 adults, diet-related practices were assessed in four domains, meal pattern', eating rate', intra-meal fluid intake', and meal-to-sleep interval', using a pretested questionnaire. LCA was applied to identify classes of diet-related practices. We defined GERD as the presence of heartburn sometimes, often or always.Key ResultsThe prevalence of GERD in the study population was 23.5% (n=1120). We identified two distinct classes of meal patterns: regular' and irregular', three classes of eating rates: moderate', moderate-to-slow', and moderate-to-fast', two major classes of fluid ingestion with meals: moderate' and much intra-meal drinking', and two classes regarding the interval between meals and sleeping: short' and long meal-to-sleep' interval. After adjustment for potential confounders, subjects with irregular meal pattern' had higher odds of GERD compared with subjects with regular meal pattern' (OR: 1.21; 1.00-1.46). However, when taking into account BMI, the association disappeared. Long meal-to-sleep interval' was inversely associated with GERD compared with short meal-to-sleep interval' (OR: 0.73; 95% CI: 0.57-0.95). Eating rate' and intra-meal fluid intake' were not significantly associated with GERD.Conclusions & InferencesOur data suggest certain associations between dietary patterns and GERD. These findings warrant evaluation in prospective studies to establish the potential value of modifications in dietary behaviors for the management of GERD.