Randomized Controlled Trial of Text Message Reminders for Increasing Influenza Vaccination
Randomized Controlled Trial of Text Message Reminders for Increasing Influenza Vaccination
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DOI：
10.1370/afm.2120
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发表时间：
2017-11-01
影响因子：
4.4
通讯作者：
Effler, Paul V.
中科院分区：
文献类型：
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作者：
Regan, Annette K.;Bloomfield, Lauren;Effler, Paul V.
目的 对于严重感染风险较高的群体，建议接种季节性流感疫苗并为其提供资助，但接种率并不理想。我们进行了一项关于流感疫苗接种短信提醒的随机对照试验。方法 在开始接种季节性流感疫苗六周后，我们在西澳大利亚州的 10 个诊所中确定了有手机号码记录的高风险患者。 32% 的选定患者在当年已接种过疫苗，因此不符合资格。在每次诊所的其余 12,354 名符合条件的患者中，一半被随机分配接受短信疫苗接种提醒（干预），其余的则不接受短信（对照）。发送短信后大约 3 个月（研究期），从患者的电子病历中提取疫苗接种数据。使用对数二项式回归模型计算干预组和对照组之间疫苗接种的相对风险 (RR)。 结果 干预组中 12%（6,177 人中的 769 人）和对照组中 9%（6,177 人中的 548 人）在研究期间接种了疫苗，SMS 使相对增加了 39%（RR = 1.39；95% CI， 1.26-1.54）。每发送 29 条短信（费用为 3.48 美元），就会有 1 名高危患者获得免疫接种。对于 5 岁以下的儿童，观察到的效果最大，如果他们的父母收到短信提醒，他们的孩子接种疫苗的可能性会增加两倍以上（RR = 2.43；95% CI，1.79-3.29）。 结论 我们发现短信提醒是一种适度有效、低成本的方法，可提高高危患者中季节性流感疫苗的覆盖率。
PURPOSE Seasonal influenza vaccine is recommended and funded for groups at higher risk of serious infection, but uptake is suboptimal. We conducted a randomized controlled trial of short message service (SMS) reminders for influenza vaccination.METHODS Six weeks after seasonal influenza vaccinations began, we identified high-risk patients who had a mobile telephone number on record at 10 practices in Western Australia. Thirty-two percent of the selected patients had already been vaccinated in the current year and were ineligible. Of the remaining 12,354 eligible patients at each practice one-half were randomly assigned to receive a vaccination reminder by SMS (intervention) and the rest received no SMS (control). Approximately 3 months after the SMS was sent (the study period), vaccination data were extracted from the patients' electronic medical records. Log-binomial regression models were used to calculate the relative risk (RR) of vaccination between the intervention and control group.RESULTS Twelve-percent (769 of 6,177) of the intervention group and 9% (548 of 6,177) of the control group were vaccinated during the study period, a 39% relative increase attributable to the SMS (RR = 1.39; 95% CI, 1.26-1.54). For every 29 SMSs sent, costing $3.48, 1 additional high-risk patient was immunized. The greatest effect was observed for children younger than 5 years, whose parents were more than twice as likely to have their child vaccinated if they received a SMS reminder (RR = 2.43; 95% CI, 1.79-3.29).CONCLUSION We found SMS reminders to be a modestly effective, low-cost means to increase seasonal influenza vaccine coverage among high-risk patients.