[Duodenal neuroendocrine tumors].

[Duodenal neuroendocrine tumors].
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十二指肠神经内分泌肿瘤.

DOI:
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发表时间:
2019
期刊:
Khirurgiia
影响因子:
--
通讯作者:
E. D. Litovchenko
E. D. Litovchenko
中科院分区:
--
文献类型:
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作者:
A. Alekberzade;N. Krylov;T. Garmanova;R. Shahbazov;F. Azari;K. S. Zuykova;E. D. Litovchenko

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近几十年来,十二指肠神经内分泌肿瘤的发病率显著增加.这些肿瘤有5种组织学类型:胃泌素瘤(50-60%),生长抑素产生肿瘤(15%),含非活性降钙素的肿瘤(20%),低分化神经内分泌癌(<3%)和神经节细胞性副神经节瘤(<2%)。肿瘤多位于十二指肠球部和球后部,20%位于壶腹周围。治疗策略取决于肿瘤的大小、定位、组织学分类、阶段和类型。一般认为,内镜下切除位于十二指肠乳头上方的小的非活动性肿瘤(G1)是允许的。大多数其他肿瘤需要手术切除。各种外科医生的个人经验受到小群体患者的限制。因此,有必要总结结果以选择最佳治疗方法。
Significant augmentation of the incidence of duodenal neuroendocrine tumors duodenum has been observed in recent decades. There are 5 histological types of these tumors: gastrinoma (50-60%), somatostatin-producing tumor (15%), inactive serotonin-containing tumors (20%), poorly differentiated neuroendocrine carcinoma (<3%) and gangliocytic paraganglioma (<2%). The majority of tumors are localized within the bulb and postbulbar part of duodenum, 20% are found in periampular area. Treatment strategy depends on dimensions, localization, histological class, stage and type of tumor. It is believed that endoscopic resection is permissible for small inactive tumors (G1) located above major duodenal papilla. The majority of other neoplasms requires surgical resection. Personal experience of various surgeons is limited by small group of patients. Therefore, it is necessary to summarize results for selection of optimal treatment.
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