FEATHER FORMATION IN HETEROTOPICALLY GRAFTED TERMINAL PARTS OF THE LEG BUD IN CHICKEN EMBRYOS
FEATHER FORMATION IN HETEROTOPICALLY GRAFTED TERMINAL PARTS OF THE LEG BUD IN CHICKEN EMBRYOS
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DOI：
10.1002/jez.1401420125
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发表时间：
1959-01-01
影响因子：
--
通讯作者：
CAMOSSO, M
中科院分区：
文献类型：
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作者：
AMPRINO, R;CAMOSSO, M
在不同的实验条件下，将后肢芽的顶端部分异位移植到鸡胚胎的翅膀或侧翼（St.21至24），鳞片和羽毛原基在覆盖跖骨和/或脚趾的皮肤上形成，这些皮肤由植入物发育而来。羽毛细菌通常来自鳞片原基的远端脊，但也来自趾垫的乳头，或脚趾皮肤中通常没有鳞片和乳头的区域。羽毛原基的发育和生长与正常羽毛相同。我们暂时提出以下建议来解释这些结果：在两个连续的发育阶段中，不同的诱导影响会到达移植物的皮肤，(1)在移植物的深层结构中产生的刺激，会诱导皮肤上的鳞片和乳头状原基的发育；(2)来自移植物床的深层结构（翅膀或侧翼的组织）的刺激，通过中间组织到达移植物，并在已经确定正常鳞片模式的皮肤中引发羽毛细菌的形成。
Under various experimental conditions in which the apical portion of the hind-limb bud is heterotopically grafted to the wing or to the flank in chicken embryos (St.21 to 24), scale as well as feather primordia form in the skin covering the metatarsus and/or the toes which develop from the implant. Feather germs form in general from the distal ridge of the scale primordia, but also from the papillae of the toe pads, or in areas of the toe skin which normally is free from scales and papillae. The feather primordia undergo development and growth identical to that of normal feathers. The following suggestion is tentatively advanced to interpret these results2 distinct sets of inductive influences reach the skin of the graft in 2 successive developmental stages, (1) stimuli arising in the deep structures of the graft, which induce the development of scale and papillae primordia in the overlying skin, (2) stimuli originating in the deep structures of the bed of the graft (tissues of the wing or the flank) which reach the graft through the intervening tissues and elicit the formation of feather germs in the skin whose normal scale pattern is already determined.