Incidence and effect of early postoperative ventricular arrhythmias after congenital heart surgery
Incidence and effect of early postoperative ventricular arrhythmias after congenital heart surgery
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DOI：
10.1016/j.hrthm.2018.11.032
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发表时间：
2019-05-01
期刊：
影响因子：
5.5
通讯作者：
Kannankeril, Prince J.
中科院分区：
文献类型：
--
作者：
Fuchs, Sarah R.;Smith, Andrew H.;Kannankeril, Prince J.
背景：小儿先天性心脏病（CHD）手术后心律失常是一种已知的发病原因，并与死亡率相关。CHD术后早期室性心律失常（VA）的综合评价尚未报道。结论我们试图确定CHD术后住院VA的发生率，并评估术后住院期间这种心律失常的临床相关性。方法2007年9月至2016年12月在我们中心接受CHD手术的患者前瞻性入选。单变量和多变量分析被用来评估术后VA和住院死亡率之间的关联，调整术后体外膜肺氧合和第1阶段单心室姑息operations.RESULTS一个共2503术后疗程在1835例患者。共有464例（18.5%）VA，其中135例（29.1%）接受了治疗。单形性室性心动过速是最常治疗的室性心律失常（TVA; n 591 [62.3%]）。TVA与术后体外膜肺氧合增加相关（13.3% vs 5.5%; P
BACKGROUND Postoperative arrhythmias after pediatric congenital heart disease (CHD) surgery are a known cause of morbidity and are associated with mortality. A comprehensive evaluation of early postoperative ventricular arrhythmias (VAs) after CHD surgery has not been reported.OBJECTIVES We sought to determine the incidence of in-hospital VAs after CHD surgery and assess the clinical relevance of this arrhythmia during the postoperative hospital course.METHODS Patients undergoing CHD surgery at our center from September 2007 through December 2016 were prospectively enrolled. Univariate and multivariate analysis was used to assess the association between postoperative VAs and in-hospital mortality, adjusting for postoperative extracorporeal membrane oxygenation and stage 1 single ventricle palliation operations.RESULTS A total of 2503 postoperative courses in 1835 patients were included. In all, 464 (18.5%) had VAs, of whom 135 (29.1%) received treatment. Monomorphic ventricular tachycardia was the most frequently treated ventricular arrhythmia (TVA; n591 [62.3%]). TVAs were associated with increased postoperative extracorporeal membrane oxygenation (13.3% vs 5.5%; P