Mechanisms of pain
Mechanisms of pain
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DOI：
10.1073/pnas.211373398
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发表时间：
2001-10-09
影响因子：
11.1
通讯作者：
Zhang, X
中科院分区：
文献类型：
--
作者：
Stucky, CL;Gold, MS;Zhang, X
持续性或慢性疼痛是人们寻求医疗护理的主要原因，但目前的治疗方法要么不足以治疗某些类型的疼痛，要么会导致无法忍受的副作用。最近，疼痛神经生物学家已经确定了许多导致疼痛起始和维持的细胞和分子过程。了解这些潜在的机制为在不久的将来开发更有效、更具体的止痛疗法带来了巨大的希望。
Persistent or chronic pain is the primary reason people seek medical care, yet current therapies are either inadequate for certain types of pain or cause intolerable side effects. Recently, pain neurobiologists have identified a number of cellular and molecular processes that lead to the initiation and maintenance of pain. Understanding these underlying mechanisms has given significant promise for the development of more effective, more specific pain therapies in the near future.