New folds of plant lectins.

New folds of plant lectins.
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植物凝集素的新折叠。

DOI:
10.1016/s0959-440x(97)80071-1
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发表时间:
1997
影响因子:
6.8
通讯作者:
Wright,CS
Wright,CS
中科院分区:
生物学2区
文献类型:
--
作者:
Wright,CS

文献摘要

被引文献

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在最近确定的凝集素的晶体结构中,雪花莲凝集素,jacalin和苋菜红-代表新的凝集素家族。它们的多肽折叠具有非常相似的特征,并且仅由β结构组成。通过假三重对称相互关联的自主折叠的β-折叠子域组装以形成β-棱柱或β-桶结构,其通过疏水核稳定。
Among the crystal structures of lectins determined recently, three — snowdrop lectin, jacalin and amaranthin — represent new lectin families. Their polypeptide folds share remarkably similar features and consist exclusively of β structure. Autonomously folded β-sheet subdomains, inter-related by a pseudothreefold symmetry, assembly to form β-prism or β-barrel structures which are stabilized by a hydrophobic core.