The role of nucleation in patterning microtubule networks.
The role of nucleation in patterning microtubule networks.
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发表时间：
1998-08
影响因子：
4
通讯作者：
A. Hyman;E. Karsenti
中科院分区：
文献类型：
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作者：
A. Hyman;E. Karsenti
微管成核的控制对于细胞中的许多微管依赖性过程是重要的。传统上，研究集中在微管从中心体成核。然而，很明显，微管可以从非中心体依赖性位点成核。在这篇综述中，我们讨论了非中心体依赖的微管成核的微管模式的形成的后果，集中在有丝分裂纺锤体的组装。
Control of microtubule nucleation is important for many microtubule dependent processes in cells. Traditionally, research has focused on nucleation of microtubules from centrosomes. However, it is clear that microtubules can nucleate from non-centrosome dependent sites. In this review we discuss the consequences of non-centrosome dependent microtubule nucleation for formation of microtubule patterns, concentrating on the assembly of mitotic spindles.