Revisiting quantitative multi-parametric MRI of benign prostatic hyperplasia and its differentiation from transition zone cancer
Revisiting quantitative multi-parametric MRI of benign prostatic hyperplasia and its differentiation from transition zone cancer
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DOI：
10.1007/s00261-019-01936-1
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发表时间：
2019-06-01
影响因子：
2.4
通讯作者：
Oto, Aytekin
中科院分区：
文献类型：
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作者：
Chatterjee, Aritrick;Gallan, Alexander J.;Oto, Aytekin
目的探讨不同类型良性前列腺增生（BPH）的多参数MRI（mpMRI）表现及定量mpMRI对前列腺癌（PCa）与BPH鉴别诊断的有效性。术前行T2加权、多回波T2加权、弥散加权和动态增强扫描。移行区前列腺癌和前列腺增生（囊性，腺性或间质性），并与MRI匹配。定量mpMRI指标：采用经验数学模型测量T2、ADC和DCE-MRI参数。
PurposeThis study investigates the multiparametric MRI (mpMRI) appearance of different types of benign prostatic hyperplasia (BPH) and whether quantitative mpMRI is effective in differentiating between prostate cancer (PCa) and BPH.Materials and methodsPatients (n=60) with confirmed PCa underwent preoperative 3T MRI. T2-weighted, multi-echo T2-weighted, diffusion weighted and dynamic contrast enhanced images (DCE) were obtained prior to undergoing prostatectomy. PCa and BPH (cystic, glandular or stromal) were identified in the transition zone and matched with MRI. Quantitative mpMRI metrics: T2, ADC and DCE-MRI parameters using an empirical mathematical model were measured.ResultsADC values were significantly lower (p