Isolation and structure elucidation of a new amphidinol with a truncated polyhydroxyl chain from Amphidinium klebsii

Isolation and structure elucidation of a new amphidinol with a truncated polyhydroxyl chain from Amphidinium klebsii
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DOI:
10.1016/j.tet.2005.07.004
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发表时间:
2005-09-05
期刊:
影响因子:
2.1
通讯作者:
Fujita, T
Fujita, T
中科院分区:
化学3区
文献类型:
--
作者:
Morsy, N;Matsuoka, S;Fujita, T

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从养殖的克氏双鞭毛藻(Amphiddium Klebsii)中分离得到一个具有最短碳链和最短硫酸酯的多烯-多羟基结构的二烷醇(AM7)新成员。AM7具有溶血和抗真菌活性。根据二维核磁共振数据结合CID-MS/MS实验确定了该化合物的结构。(C)2005爱思唯尔有限公司。保留所有权利。
A new member of amphidinols (AM7) possessing a polyene-polyhydroxyl structure with the shortest carbon backbone and sulfate ester was isolated from the cultured dinoflagellate, Amphidinium klebsii. AM7 showed hemolytic and antifungal activities. The structure was elucidated on the basis of 2D NMR data in combination with CID MS/MS experiments. (c) 2005 Elsevier Ltd. All rights reserved.