Measurement of kidney function
Measurement of kidney function
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DOI：
10.1016/j.mcna.2004.11.009
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发表时间：
2005-05-01
影响因子：
5.9
通讯作者：
Levey, AS
中科院分区：
文献类型：
--
作者：
Stevens, LA;Levey, AS
准确估计肾功能是检测、评估和治疗慢性肾脏疾病（CKD）的核心。肾小球滤过率（Glomerular filtration rate， GFR）被广泛认为是肾功能的最佳综合指标，因此它构成了CKD定义和分类系统的基础。GFR在临床实践中不能直接测量，估计GFR的方法多种多样，各有其优点和局限性。目前推荐的方法是使用基于血清肌酐的估计方程，并结合人口统计学和临床变量。
Accurate estimation of kidney function is central to the detection, evaluation, and treatment of chronic kidney disease (CKD). Glomerular filtration rate (GFR) is widely accepted as the best overall measure of kidney function and as such it forms the basis of the definition and classification system for CKD. GFR cannot be measured directly in clinical practice and multiple methods are used to estimate GFR, all of which have their strengths and limitations. The current recommended method is to use estimating equations based on serum creatinine and which incorporate demographic and clinical variables.