Antibiotic resistance of faecal Escherichia coli from healthy volunteers from eight developing countries
Antibiotic resistance of faecal Escherichia coli from healthy volunteers from eight developing countries
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DOI：
10.1093/jac/dkh448
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发表时间：
2004-11-01
影响因子：
5.2
通讯作者：
Stobberingh, EE
中科院分区：
文献类型：
--
作者：
Nys, S;Okeke, IN;Stobberingh, EE
目的：确定耐抗生素粪便大肠杆菌的流行率从城市（U）地区在肯尼亚，墨西哥，秘鲁和菲律宾，和非城市（NU）地点在库拉考，墨西哥，委内瑞拉，加纳，津巴布韦和Philippine.Methods：粪便样本的成年志愿者（n=1290）进行了分析，在一个实验室的耐抗生素大肠杆菌的存在。结果：受试者平均年龄为35岁，以女性为主，平均年龄为35岁，平均年龄为35岁。环丙沙星耐药率在1%-63%之间：在亚洲和南美洲的城市人群中发现的百分比最高。在秘鲁和菲律宾（U和NU），庆大霉素耐药率> 20%。头孢唑林耐药率在菲律宾城市最高（25%）。氨苄青霉素、土霉素和甲氧苄啶在亚洲、非洲和南美洲城市地区的流行率分别高于非城市地区（P
Objectives: To determine the prevalence of antibiotic-resistant faecal Escherichia coli from adult volunteers from urban (U) areas in Kenya, Mexico, Peru and the Philippines, and non-urban (NU) locations in Curacao, Mexico, Venezuela, Ghana, Zimbabwe and the Philippines.Methods: Faecal samples of adult volunteers (n=1290) were analysed in one laboratory for the presence of antimicrobial-resistant E. coli using Eosin Methylene Blue agar plates containing, respectively, ampicillin, oxytetracycline, cefazolin, ciprofloxacin, gentamicin, chloramphenicol and trimethoprim at breakpoint concentrations.Results: The mean age of the volunteers was similar to35 years; most of them were female. Ciprofloxacin resistance was in the range 1%-63%: the highest percentages were found in the urban populations of Asia and South America. In Peru and the Philippines (U and NU), the prevalence of gentamicin resistance was >20%. Cefazolin resistance was the highest in the urban Philippines (25%). Higher prevalences for ampicillin, oxytetracycline and trimethoprim were found for urban areas compared with non-urban ones of Asia, Africa and South America, respectively (P