Magnetic circular dichroism of biological molecules.
Magnetic circular dichroism of biological molecules.
复制标题
生物分子的磁圆二色性。
DOI：
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
B. Holmquist
中科院分区：
文献类型：
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作者：
J. Sutherland;B. Holmquist
磁性圆二色性（MCD）现在已经发展到它应该是所有使用可见光，紫外线和近红外光谱来探测生物分子结构和功能的科学家的几种工具之一。与其他光谱技术一样，该方法的多样性很大，应用范围从分析分析（它可能是蛋白质中色氨酸的最直接方法）扩展到卟啉塞曼分裂的理论描述。本文介绍了MCD和几个密切相关的实验，总结了MCD的理论，从实际应用的角度来解决生物化学问题，调查可用的仪器，并回顾了文献的MCD的主要类别的生物分子。更专业的综述描述了MCD在生物领域特定领域的应用（24，48，67，n，78，135，153，164，189）。
Magnetic circular dichroism (MCD) has now been developed to the point where it should be one of the several tools at the disposal of all scientists who use visible, ultraviolet, and near infrared spectroscopies to probe the structure and function of biological molecules. As in other spectral techniques, the diversity of the method is large, with applica tions extending from analytical analysis (it provides perhaps the most direct method for tryptophan in proteins) to the theoretical description of Zeeman splitting in the porphyrins. This review describes MCD and several closely related experiments, summarizes the theory of MCD from the viewpoint of practical applications to biochemical problems, surveys available instrumentation, and reviews the literature on the MCD of major classes of biological molecules. More specialized reviews describe the use of MCD in particular areas in the biological realm (24, 48, 67, n, 78, 135, 153, 164, 189).