Support vector machines for predicting protein structural class.
Support vector machines for predicting protein structural class.
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DOI:
10.1186/1471-2105-2-3
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发表时间:
2001
影响因子:
3
通讯作者:
Zhou GP
中科院分区:
文献类型:
--
作者:
Cai YD;Liu XJ;Xu X;Zhou GP
We apply a new machine learning method, the so-called Support Vector Machine method, to predict the protein structural class. Support Vector Machine method is performed based on the database derived from SCOP, in which protein domains are classified based on known structures and the evolutionary relationships and the principles that govern their 3-D structure. High rates of both self-consistency and jackknife tests are obtained. The good results indicate that the structural class of a protein is considerably correlated with its amino acid composition. It is expected that the Support Vector Machine method and the elegant component-coupled method, also named as the covariant discrimination algorithm, if complemented with each other, can provide a powerful computational tool for predicting the structural classes of proteins.
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DOI:
10.1002/prot.340160109
发表时间:
1993-05-01
期刊:
PROTEINS-STRUCTURE FUNCTION AND GENETICS
影响因子:
--
作者:
DUBCHAK, I;HOLBROOK, SR;KIM, SH
通讯作者:
KIM, SH
DOI:
10.1073/pnas.97.1.262
发表时间:
2000-01-04
影响因子:
11.1
作者:
Brown, MPS;Grundy, WN;Haussler, D
通讯作者:
Haussler, D
影响因子:
7.5
作者:
CORTES, C;VAPNIK, V
通讯作者:
VAPNIK, V
DOI:
10.1002/prot.340210406
发表时间:
1995-04-01
期刊:
PROTEINS-STRUCTURE FUNCTION AND GENETICS
影响因子:
--
作者:
CHOU, KC
通讯作者:
CHOU, KC
DOI:
10.1023/a:1020713915365
发表时间:
1998-11-01
期刊:
JOURNAL OF PROTEIN CHEMISTRY
影响因子:
--
作者:
Zhou, GP
通讯作者:
Zhou, GP