Serial time-encoded amplified microscopy (STEAM) based on a stabilized picosecond supercontinuum source.
Serial time-encoded amplified microscopy (STEAM) based on a stabilized picosecond supercontinuum source.
复制标题
DOI：
10.1364/oe.19.015810
复制
发表时间：
2011-08
期刊：
影响因子：
3.8
通讯作者：
Chi Zhang;Y. Qiu;Rui Zhu;K. Wong;K. Tsia
中科院分区：
文献类型：
--
作者：
Chi Zhang;Y. Qiu;Rui Zhu;K. Wong;K. Tsia
超连续介质（SC）等宽带光源的时间稳定性是实现高性能超快串行时间编码放大显微镜（STEAM）的关键因素。由于长脉冲SC（皮秒到纳秒）的产生通常会导致具有显著脉冲间波动的超宽带频谱，因此到目前为止，STEAM中只使用了具有更好时间稳定性的超短脉冲SC（飞秒）源。在这里，我们报告了一种简单的方法来实现皮秒SC稳定性的主动控制，并帮助将SC在STEAM中的适用性从飞秒扩展到皮秒甚至纳秒。我们通过实验证明了使用cw触发的皮秒SC源在4.9 MHz帧速率下稳定的单次STEAM成像。这种cw稳定的SC可以大大降低镜头间的波动，从而显著提高STEAM图像质量。
Temporal stability of the broadband source, such as supercontinuum (SC), is the key enabling factor for realizing high performance ultrafast serial time-encoded amplified microscopy (STEAM). Owing to that the long-pulse SC (picosecond to nanosecond) generation generally results in an ultrabroadband spectrum with significant pulse-to-pulse fluctuation, only the ultrashort-pulse (femtosecond) SC sources, which offer better temporal stability, have been employed in STEAM so far. Here we report a simple approach to achieve active control of picosecond SC stability and to help extend the applicability of SC in STEAM from the femtosecond to the picosecond or even nanosecond regimes. We experimentally demonstrate stable single-shot STEAM imaging at a frame rate of 4.9 MHz using the CW-triggered picosecond SC source. Such CW-stabilized SC can greatly reduce the shot-to-shot fluctuation, and thus improves the STEAM image quality significantly.