Detection of HBsAg in Coagulation Factor IX Concentrates
Detection of HBsAg in Coagulation Factor IX Concentrates
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凝血因子 IX 浓缩物中 HBsAg 的检测
DOI：
10.1046/j.1537-2995.1977.17177128883.x
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发表时间：
1977
期刊：
影响因子：
2.9
通讯作者：
A. Simmons
中科院分区：
文献类型：
--
作者：
M. O'Connor;E. S. Meek;A. Simmons
在两种商业凝血因子浓缩物：Proplex （Hyland）和Konyne （Cutter）中检测HBsAg。Proplex样品HBsAg检测阳性，Konyne样品HBsAg检测阴性。然而，免疫电镜显示，在两种制剂中都有聚集的小球体HBsAg，并且在几种制剂中可以看到片层型链。
HBsAg was detected in two commercial clotting factor concentrates: Proplex (Hyland) and Konyne (Cutter). HBsAg was positive by RIA in samples of Proplex but not Konyne. Immune‐electron microscopy, however, demonstrated clumped small spheres of HBsAg in both preparations, and lamellar‐type strands were seen in several preparations.