ELLIPSOIDAL SHELL SUBTRACTION MODEL OF RIGHT VENTRICULAR VOLUME - COMPARISON WITH REGIONAL FREE WALL DIMENSIONS AS INDEXES OF RIGHT VENTRICULAR-FUNCTION
ELLIPSOIDAL SHELL SUBTRACTION MODEL OF RIGHT VENTRICULAR VOLUME - COMPARISON WITH REGIONAL FREE WALL DIMENSIONS AS INDEXES OF RIGHT VENTRICULAR-FUNCTION
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DOI：
10.1161/01.res.67.6.1427
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发表时间：
1990-12-01
影响因子：
20.1
通讯作者：
RANKIN, JS
中科院分区：
文献类型：
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作者：
FENELEY, MP;ELBEERY, JR;RANKIN, JS
在8只离体和3只离体泵灌注犬心脏标本以及9只清醒犬中，使用脉冲传输声显微术测量左心室的基底-心尖（a）、前后（B）和无间隔壁（c）直径以及右心室的无间隔壁直径（d）。在三个灌注心脏和四个切除的心脏，右心室游离壁区域段长度和段面积也进行了评估。所有离体心脏均用腔内球囊直接测量双心室容积。当左室球囊容积保持不变时，右室游离壁尺寸与右室球囊容积之间呈高度线性关系。然而，随着左心室容积的增加，这些关系保持线性，但逐渐向上移动，表明右心室游离壁尺寸和左心室腔容积之间存在独立的关系。椭球壳减法模型（π/ 6.cntdot. ABD减去右心室游离壁体积）来从心脏尺寸估计右心室腔室体积。用这种方法，在计算的右心室容积和右心室球囊容积之间观察到高度线性关系（平均r = 0.99 ± 0.99）。0.01）。此外，这种关系似乎是独立的左心室球囊容积的变化。与壳减法模型，动态右心室容积计算在9个清醒的狗，并在4个，每搏输出量来自尺寸与超声流量探头测量的右心室每搏输出量进行了比较。观察到高度线性关系，表明壳减法在体内的准确性。然后评价右心室收缩末期压力-容积和每搏功/舒张末期容积的关系，证明两者在右心室中都是高度线性的（两者的平均值r = 0.99 ± 0.99）。0.01）。因此，壳减法模型允许简单估计完整心脏中的动态右心室容积，并有助于评估体内右心室性能。
Pulse-transit sonomicrometry was used to measure the base-apex (a), anteroposterior (b), and septal-free wall (c) diameters of the left ventricle and the septal-free wall diameter of the right ventricle (d) in eight excised and three isolated, pump-perfused canine heart preparations, as well as in nine conscious dogs. In the three perfused hearts and in four of the excised hearts, right ventricular free wall regional segment lengths and segment area also were assessed. Biventricular volumes were measured directly with intracavitary balloons in all isolated hearts. When left ventricular balloon volume was held constant, relations between right ventricular free wall dimensions and right ventricular balloon volume were highly linear. With increments in left ventricular volume, however, these relations remained linear but shifted progressively upward, indicating an independent relation between right ventricular free wall dimensions and left ventricular cavitary volume. An ellipsoidal shell subtraction model (.pi./6 .cntdot. abd minus right ventricular free wall volume) was developed to estimate right ventricular cavitary volume from cardiac dimensions. With this method, a highly linear relation was observed between calculated right ventricular volume and right ventricular balloon volume (mean r = 0.99 .+-. 0.01). Moreover, this relation appeared to be independent of changes in left ventricular balloon volume. With the shell subtraction model, dynamic right ventricular volume was computed in nine conscious dogs, and in four, stroke volume derived from dimensions was compared with right ventricular stroke volume measured with ultrasonic flow probes. A highly linear relation was observed, suggesting the accuracy of the shell subtraction method in vivo. Right ventricular end-systolic pressure-volume and stroke work/end-diastolic volume relations then were evaluated, and both proved to be highly linear in the right ventricle (both mean r = 0.99 .+-. 0.01). Thus, the shell subtraction model allows a simple estimate of dynamic right ventricular volume in the intact heart and facilitates assessment of right ventricular performance in vivo.