[Systemic vasculitic neuropathy diagnosed by means of (18)F-FDG PET CT].
[Systemic vasculitic neuropathy diagnosed by means of (18)F-FDG PET CT].
复制标题
(18)F-FDG PET CT诊断系统性血管炎性神经病[J].
DOI：
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
T. Kanda
中科院分区：
文献类型：
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作者：
S. Fujikawa;M. Omoto;J. Ogasawara;M. Koga;M. Kawai;T. Kanda
我们报告一个43岁的男子经历麻木在远端部分的双腿，其进展在接下来的两个月。神经学检查显示两腿远端部分感觉亢进和肌肉无力。血液检查及全身CT检查未见异常。腓肠神经和腓骨短肌的组织病理学检查显示髓鞘神经纤维减少，髓鞘卵泡散在，神经外膜血管闭塞，肌束小动脉周围有炎症细胞。这些发现表明属于非全身性血管神经性病变（NSVN）的范畴。（18）氟脱氧葡萄糖（FDG）正电子发射断层扫描（PET）显示FDG在直肠摄取增加。直肠粘膜活检组织病理标本中，小动脉周围可见炎性细胞浸润伴纤维蛋白样坏死。结果提示诊断为全身性血管炎。NSVN的诊断可能取决于诊断程序的敏感性，（18）F-FDG PET CT可能是检测中小型血管炎的有用工具。
We report a 43-year-old man experienced numbness in the distal portion of both legs, which progressed over following two months. Neurological examination showed hypesthesia and muscle weakness in the distal portion of both legs. No abnormal findings were seen on blood test and whole-body contrast enhanced computed tomography (CT). Histopathological findings of the sural nerve and the peroneus brevis muscle showed decreased myelinated nerve fibers with scattered myelin ovoids, vascular occlusion in the epineurium, and inflammatory cell around the arteriole in the muscle bundle. These findings suggested falling in the category as non-systemic vasculitic neuropathy (NSVN). (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) revealed the increase of FDG uptake in the rectum. Inflammatory cell infiltration was found around the arteriole with fibrinoid necrosis in the histopathological specimen of the rectal mucosal biopsy. This result represented the diagnosis as systemic vasculitis. The diagnosis of NSVN may depend on the sensitivity of diagnostic procedure, and (18)F-FDG PET CT might be a useful tool to detect small or medium-sized vasculitis.
影响因子：
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作者：
Jennette, J. C.;Falk, R. J.;Watts, R. A.
通讯作者：
Watts, R. A.