CELL-DIVISION IN VOMERONASAL ORGAN OF ADULT MOUSE
CELL-DIVISION IN VOMERONASAL ORGAN OF ADULT MOUSE
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DOI：
10.1016/0006-8993(78)90616-9
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发表时间：
1978-01-01
期刊：
影响因子：
2.9
通讯作者：
RAISMAN, G
中科院分区：
文献类型：
--
作者：
BARBER, PC;RAISMAN, G
用[~ 3 H]胸腺嘧啶核苷标记成年小鼠犁鼻神经感觉上皮中的分裂细胞群。这些细胞定位于与纤毛呼吸上皮交界的上皮区域。随着胸苷给药后存活时间的增加，标记细胞逐渐远离边界区域。具有标记的细胞核的细胞簇形成松散的柱，由标记的受体细胞组成，但此外，直接覆盖的支持细胞核也被标记。胸苷给药后56天，标记细胞簇与上皮边界的距离相当于上皮片总宽度的约1/5。在102天时，位置几乎没有进一步变化。目前尚不清楚这在多大程度上代表了一个周转过程，而不是通过在边缘增生的上皮细胞的持续生长。
Using [3H]thymidine labeling a population of dividing cells in the vomeronasal neurosensory epithelium of the adult mouse was demonstrated. These cells were localized in the regions of the epithelium adjacent to its boundaries with the ciliated respiratory epithelium. With increasing survival times after thymidine administration, the labeled cells became situated progressively further away from the boundary region. The cluster of cells with labeled nuclei formed a loose column, consisting of labeled receptor cells, but in addition the immediately overlying supporting cell nuclei were also labeled. By 56 days after thymidine administration the cluster of labeled cells was separated from the epithelial boundary by a distance equivalent to about 1/5 of the total width of the epithelial sheet. There was little further change in position at 102 days. It is not clear to what extent this represents a turnover process as opposed to a continuing growth of the epithelium by accretion at the edges.