Management of complicated multirecurrent pterygia using multimicroporous expanded polytetrafluoroethylene.
Management of complicated multirecurrent pterygia using multimicroporous expanded polytetrafluoroethylene.
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DOI：
10.1136/bjophthalmol-2012-302784
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发表时间：
2013-06
期刊：
影响因子：
--
通讯作者：
Moon NJ
中科院分区：
文献类型：
--
作者：
Kim KW;Kim JC;Moon JH;Koo H;Kim TH;Moon NJ
评价多微孔膨胀聚四氟乙烯（e-PTFE）插入治疗复杂多复发性翼状胬肉的效果。本研究共招募了62例伴有睑粘连或运动受限相关性双眼复视的多发复发性翼状胬肉患者的62只眼睛。所有患者行翼状胬肉切除，应用0.033%丝裂霉素C，羊膜移植和自体结膜缘移植。A组30眼术中在移植的羊膜与结膜之间置入多微孔e-PTFE， B组32眼术中不置入。主要观察指标为睑粘连形成、运动受限、双眼复视、结膜充血主观评分及术后翼状胬肉复发。平均随访17.2±2.3个月，A组患者术后睑粘连形成、运动受限、复视、结膜充血明显改善（p值分别为0.000、0.000、0.008、0.000）。A组术后睑粘连形成、运动受限、结膜充血明显少于B组（p分别=0.024、0.027、0.000）。术后A组角膜复发率为1眼（3.3%），显著低于B组8眼（25%）（p=0.027）。多微孔e-PTFE插入可能为治疗难治性复杂多复发性翼状胬肉提供新的途径。
To evaluate the efficiency of multimicroporous expanded polytetrafluoroethylene (e-PTFE) insertion in complicated multirecurrent pterygia. A total of 62 eyes from 62 patients with a multirecurrent pterygium associated with symblepharon or motility restriction-related binocular diplopia were recruited. All eyes underwent pterygia excision followed by application of 0.033% mitomycin C, amniotic membrane transplantation and conjunctival limbal autograft. Multimicroporous e-PTFE was then inserted intraoperatively in 30 eyes between the transplanted amniotic membrane and the conjunctiva (group A), but not inserted in the other 32 eyes (group B). The main outcome measures were symblepharon formation, motility restriction, binocular diplopia, subjective score of conjunctival hyperaemia and postoperative pterygium recurrence. In the mean follow-up period of 17.2±2.3 months, symblepharon formation, motility restriction, diplopia and conjunctival hyperaemia were significantly improved after surgery in group A patients (p=0.000, 0.000, 0.008 and 0.000, respectively). Postoperative symblepharon formation, motility restriction and conjunctival hyperaemia were significantly less in group A compared to group B (p=0.024, 0.027 and 0.000, respectively). After surgery, corneal recurrence developed in one eye (3.3%) from group A, which was significantly lower than the eight eyes (25%) from group B (p=0.027). Multimicroporous e-PTFE insertion may provide a novel approach for treating intractable complicated multirecurrent pterygia.
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DOI：
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发表时间：
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期刊：
ACTA OPHTHALMOLOGICA SCANDINAVICA
影响因子：
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作者：
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发表时间：
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影响因子：
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