A prospective multi-center study evaluating periodontal regeneration for class II furcation invasions and intrabony defects after treatment with a bioabsorbable barrier membrane: 1-year results
A prospective multi-center study evaluating periodontal regeneration for class II furcation invasions and intrabony defects after treatment with a bioabsorbable barrier membrane: 1-year results
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DOI：
10.1902/jop.1996.67.7.641
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发表时间：
1996-07-01
影响因子：
4.3
通讯作者：
Reid, T
中科院分区：
文献类型：
--
作者：
Becker, W;Becker, BE;Reid, T
这项前瞻性多中心研究的目的是评估专为牙周再生设计的可吸收屏障膜。31例II类分叉和30例两壁和三壁骨内缺损通过皮瓣清创和生物可吸收屏障膜增强治疗。根据垂直探测深度（PD）、水平探测深度（HPD）、临床附着水平（GAL）和后退的变化评价治疗效果。五个中心参与了这项研究。临床参数的变化按单个中心和中心平均值报告。所有患者都有一颗磨牙伴II类分叉或骨内缺损。基线数据在手术当天采集。在6个月和1年时收集治疗后数据。本报告基于1年的调查结果。II类分叉的平均初始PD为6.1 mm。1年时，平均PD降至3.6 mm，变化2.5 mm。这些差异具有临床和统计学显著性（P < 0.0001）。临床附着平均增加2.1mm（P < 0.0001），后退0.4mm（P < 0.04）。HPD平均变化1.8mm（P < 0.0001）。对于骨内缺损，1年时PD平均减少4.1 mm（P < 0.0001），CAL平均增加2.9 mm（P < 0.0001）。1年时，平均衰退为0.9毫米，具有统计学意义。当比较两个中心的治疗结果时，两组治疗的缺损没有差异。当比较分叉和骨内部位的基线PD时，研究中心之间存在差异。本研究的结果表明，在使用生物可吸收牙周膜治疗II类分叉和2- 3壁骨内缺损后，PD、GAL和HPD的临床和统计学显著改善。
THE PURPOSE OF THIS PROSPECTIVE MULTICENTER STUDY was to evaluate a resorbable barrier membrane designed for periodontal regeneration. Thirty-one Class II furcations and 30 two- and three-wall intrabony defects were treated by flap debridement and bioabsorbable barrier membrane augmentation. The efficacy of treatment was evaluated in terms of changes in vertical probing depth (PD), horizontal probing depth (HPD), clinical attachment levels (GAL), and recession. Five centers participated in the study. Changes in clinical parameters are reported by individual center and by the average of the centers. All patients had either one molar with a Class II furcation or an intrabony defect. Baseline data were taken on the day of surgery. Post-treatment data were collected at 6 months and 1 year. This report is based on the 1-year findings. The average initial PD for Class II furcations was 6.1 mm. At 1 year the average PD was reduced to 3.6 mm, a 2.5 mm change. These differences were clinically and statistically significant (P < 0.0001). There was an average gain of 2.1 mm of clinical attachment (P < 0.0001) and 0.4 mm of recession (P < 0.04). There was a mean of 1.8 mm change in HPD (P < 0.0001). For intrabony defects, at 1 year there was an average PD reduction of 4.1 mm (P < 0.0001) and a mean gain of CAL of 2.9 mm (P < 0.0001). At 1 year the average recession was 0.9 mm which was statistically significant. When treatment outcomes were compared between centers there were no differences for either group of treated defects. There were differences between centers when baseline PD for furcations and intrabony sites were compared. The results of this study indicate that clinically and statistically significant improvements in PD, GAL, and HPD occurred after treatment of Class II furcations and 2- to 3-wall intrabony defects with the bioabsorbable periodontal membrane.