APPLICATION OF STEREOLOGICAL PRINCIPLES TO MORPHOMETRY OF MICROCIRCULATION IN DIFFERENT TISSUES

APPLICATION OF STEREOLOGICAL PRINCIPLES TO MORPHOMETRY OF MICROCIRCULATION IN DIFFERENT TISSUES
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DOI:
10.1016/0026-2862(77)90028-0
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发表时间:
1977-01-01
影响因子:
3.1
通讯作者:
KOVALCHECK, S
KOVALCHECK, S
中科院分区:
医学3区
文献类型:
--
作者:
SCHMIDSCHOENBEIN, GW;ZWEIFACH, BW;KOVALCHECK, S

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地形因素是微循环中流体动力学事件的主要决定因素之一。已建立的体视学技术的应用是一种有效和准确的方法来获得有关各种微血管结构的定量信息。大网膜和肠系膜作为典型的二维单位进行了分析,通过这种形态测量技术,和大鼠脊髓背角肌和猫细肌肌肉作为三维结构的例子进行了分析。在猫肠系膜中,除了分析血管外,还研究了伴随的淋巴管。根据血管直径和长度密度对血管形态测量数据进行分类,从中可以计算出一些重要的形态参数。一个显着的相似性表明,在这些不同的组织的健康实验室动物的微循环的形态特征。
Topographical factors represent one of the major determinants of the hydrodynamic events in the microcirculation. The application of established stereologic techniques was an efficient and accurate way to obtain quantitative information concerning the various microvascular structures. The omentum and mesentery were analyzed as typical 2-dimensional units by such morphometric techniques, and the rat spinotrapezius and cat tenuissimus muscles were analyzed as examples of 3-dimensional structures. In the cat mesentery, in addition to an analysis of the blood vessels, a study was made of the accompanying lymphatic vessels. The vascular morphometric data were classified on the basis of vessel diameter and length density, from which a number of important morphological parameters could be calculated. A remarkable similarity was indicated in morphometric features of the microcirculation in these different tissues of healthy laboratory animals.