Deciphering the relationship between central and effector memory CD8+ T cells

Deciphering the relationship between central and effector memory CD8+ T cells
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DOI:
10.1016/s1471-4906(03)00169-8
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发表时间:
2003-08-01
影响因子:
16.8
通讯作者:
Tough, DF
Tough, DF
中科院分区:
医学1区
文献类型:
--
作者:
Tough, DF

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记忆性CD8(+)T细胞可根据其表型和分别归巢至淋巴结和非淋巴组织的潜力分为称为中央记忆细胞和效应记忆细胞的亚群。最近的两项研究,一项在人类中,一项在小鼠中,为这些亚群之间的谱系关系提供了新的见解。
Memory CD8(+) T cells can be divided into sub-populations termed central memory cells and effector memory cells based on their phenotype and potential to home to lymph nodes versus non-lymphoid tissues, respectively. Two recent studies, one in humans and one in mice, provide new insight into the lineage relationship between these sub-populations.