ASSOCIATION OF GROUP-C BETA-HEMOLYTIC STREPTOCOCCI WITH ENDEMIC PHARYNGITIS AMONG COLLEGE-STUDENTS
ASSOCIATION OF GROUP-C BETA-HEMOLYTIC STREPTOCOCCI WITH ENDEMIC PHARYNGITIS AMONG COLLEGE-STUDENTS
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DOI：
10.1001/jama.264.20.2644
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发表时间：
1990-11-28
影响因子：
120.7
通讯作者：
MURREN, D
中科院分区：
文献类型：
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作者：
TURNER, JC;HAYDEN, GF;MURREN, D
在整个2个学年中进行咽喉培养以确定非A β组是否存在。232名有咽炎症状的大学生比198名年龄匹配的无感染问题的对照组更容易分离到溶血性链球菌（NGA BHS）。将一式两份咽拭子接种到含有羊血琼脂的平板上，一个平板在5% CO2气氛中孵育，另一个平板在厌氧环境中孵育。采用乳胶凝集法对BHS进行分组。在NGA BHS中，只有C组患者的分离率显著高于对照组（26% vs 11%）。C组BHS分离株的定量菌落计数在患者中普遍高于对照组。C组BHS患者出现发热、渗出性扁桃体炎和颈前淋巴结肿大的频率明显高于咽部培养阴性的C组BHS患者。C组BHS在流行病学上与该大学生人群中的地方性咽炎相关。
Throat cultures were performed throughout 2 school years to determine whether non-group A .beta.-hemolytic streptococci (NGA BHS) could be isolated more frequently in 232 college students who had symptomatic pharyngitis than from 198 age-matched controls with noninfectious problems. Duplicate throat swabs were inoculated onto plates that contained sheep blood agar, one plate being incubated in a 5% CO2 atmosphere and the other in an anaerobic environment. The BHS were grouped using latex agglutination. Among the NGA BHS, only those from group C were isolated significantly more often among the patients compared with the controls (26% vs 11%). Quantitative colony counts of isolates of group C BHS were generally higher among patients than controls. Patients with group C BHS had fever, exudative tonsillitis, and anterior cervical adenopathy significantly more frequently than did patients who had throat cultures that were negative for group C BHS. Group C BHS were epidemiologically associated with endemic pharyngitis in this college student population.