MIDA Boronate Stabilized Polymers as a Versatile Platform for Organoboron and Functionalized Polymers
MIDA Boronate Stabilized Polymers as a Versatile Platform for Organoboron and Functionalized Polymers
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MIDA 硼酸酯稳定聚合物作为有机硼和功能化聚合物的多功能平台
DOI：
10.1021/acs.macromol.0c00665
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发表时间：
2020-05-26
期刊：
影响因子：
5.5
通讯作者：
Pan, Xiangcheng
中科院分区：
文献类型：
--
作者：
He, Congze;Pan, Xiangcheng
含硼聚合物已被证明是有用的聚合物材料。然而，含硼酸或酯的聚合物的合成由于其不稳定性和难以表征而极具挑战性。本文介绍了N-甲基亚氨基二乙酸（MIDA）作为硼酸的独特保护基来稳定含硼聚合物。合成的MIDA硼酸盐稳定聚合物对空气、水分和色谱显示出显著的稳定性。因此，它们可以用作合成其他含硼酸或含酯聚合物的通用平台。后聚合改性还通过使用该平台通过Suzuki-Miyaura偶联结合不同的功能。稳定性和多功能性使得MIDA硼酸盐稳定聚合物在与硼烷化学相关的材料和生物医学领域具有巨大的潜在应用。
Boron-containing polymers have been demonstrated to be useful polymeric materials. However, the synthesis of boronic acid- or ester-containing polymers is highly challenging due to their instability and difficult characterization. This paper introduces N-methyliminodiacetic acid (MIDA) as a unique protecting group for the boronic acid to stabilize boron-containing polymers. The synthesized MIDA boronate stabilized polymers show remarkable stability to the air, moisture, and chromatography. Therefore, they could be used as a versatile platform for synthesizing other boronic acid- or ester-containing polymers. Postpolymerization modification also incorporates different functionalities by using this platform by Suzuki-Miyaura coupling. Both stability and versatility make MIDA boronate stabilized polymers have great potential applications in material and biomedical fields associated with borane chemistry.