Transmission and tissue distribution of Pseudoloma neurophilia (Microsporidia) of zebrafish, Danio rerio (Hamilton)
Transmission and tissue distribution of Pseudoloma neurophilia (Microsporidia) of zebrafish, Danio rerio (Hamilton)
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DOI：
10.1046/j.1365-2761.2003.00467.x
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发表时间：
2003-07-01
影响因子：
2.5
通讯作者：
Bishop-Stewart, JK
中科院分区：
文献类型：
--
作者：
Kent, ML;Bishop-Stewart, JK
最近，斑马鱼作为研究脊椎动物发育遗传学基本机制的实验室模型的使用急剧增加。根据斑马鱼国际资源中心对27个斑马鱼研究设施进行的诊断检查，这种鱼最常见的疾病是神经微孢子虫病。感染最常见于脊髓和后脑。它也发生在腹根神经节和躯体肌肉中，在那里它与炎症有关。这些鱼通常严重消瘦，并可能表现出脊柱侧凸的变化。
There has recently been a dramatic increase in the use of zebrafish Danio rerio as a laboratory model to study basic mechanisms of vertebrate developmental genetics. Based on diagnostic examinations conducted through the Zebrafish International Resource Center on 27 zebrafish research facilities, the most common disease in this fish is neural microsporidiosis. The infection is most common in the spinal chord and hindbrain. It also occurs in ventral root ganglia and somatic muscle, where it is associated with inflammation. These fish are usually severely emaciated and may exhibit scoliotic changes.