Remineralization of Natural Human Carious Dentin Lesions with an Experimental Whisker-Reinforced Atraumatic Restorative Treatment Composite.
Remineralization of Natural Human Carious Dentin Lesions with an Experimental Whisker-Reinforced Atraumatic Restorative Treatment Composite.
复制标题
使用实验性晶须强化非创伤性修复治疗复合材料对天然人类龋齿牙本质病变进行再矿化。
DOI：
10.1111/jopr.12754
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发表时间：
2019
期刊：
影响因子：
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通讯作者：
Yang,Bin
中科院分区：
文献类型：
--
作者：
Zhang,Chao;Campbell,StephenD;Dickens,SabineH;Yang,Bin
目的评价一种实验性须增强非创伤性修复治疗（ART）复合材料对天然牙本质龋的再矿化作用。材料和方法采用暴露染料和手工器械制备中度牙质活性龋，用ART或树脂改性玻璃离子水合剂（RM - GIC）修复，湿切成120µm切片，每组15个切片。在拍摄横向显微x线照片并实施数字图像分析以确定“矿物质-损失-之前”后，每个切片在人工唾液溶液（pH = 7.0）中孵育4周和8周，每个工作日在脱矿溶液（pH = 4.3）中孵育1小时。重新拍摄每一段的横向显微x线照片，并确定“矿物-损失-后”。再矿化作用由[1‐（“矿物损失-事后”/“矿物损失-事前”）]× 100%计算得出。结果采用重复测量方差分析进行统计学分析，其中一个因素为受试者内部因素（时间：4周和8周），一个因素为受试者之间因素（材料：ART和RM - GIC） （α = 0.05）。结果经统计学分析，ART复合治疗的再矿化率明显高于RM - GIC （p≤0.05）。各材料再矿化4周与8周比较，差异有统计学意义（p≤0.05）。结论该实验性ART复合材料对天然牙本质龋的再矿化效果优于RM - GIC。
PurposeTo evaluate the remineralization of natural human dentin caries with an experimental whisker‐reinforced Atraumatic Restorative Treatment (ART) composite.Materials and MethodsTeeth with moderate active dentin caries were prepared with caries‐disclosing dye and hand instruments, restored with ART or resin‐modified glass ionomer cement (RM‐GIC), and then wet sliced into 120‐µm sections with 15 sections in each group. After taking transverse microradiographs and implementing digital image analysis to determine the “mineral‐loss‐before,” each section was incubated in artificial saliva solution (pH = 7.0) for 4 weeks and 8 weeks with 1 hour each workday in demineralization solution (pH = 4.3). Transverse microradiographs of each section were retaken, and the “mineral‐loss‐after” was determined. The remineralization was calculated from [1‐(“mineral‐loss‐after”/“mineral‐loss‐before”)] × 100%. Results were statistically analyzed with a repeated‐measures ANOVA with one within‐subject factor (time: 4 and 8 weeks) and one between‐subject factor (material: ART and RM‐GIC) (α = 0.05).ResultsThe statistical analysis indicated that ART composite resulted in significantly higher remineralization than the RM‐GIC (p≤ 0.05). For the remineralization of each material, there was a statistical difference between 4 weeks and 8 weeks (p≤ 0.05).ConclusionsThis experimental ART composite remineralized natural human dentin caries better than the RM‐GIC.