Health-related quality of life and psychological distress in a population-based sample of Swedish patients with inflammatory bowel disease
Health-related quality of life and psychological distress in a population-based sample of Swedish patients with inflammatory bowel disease
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DOI：
10.1080/003655202317316097
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发表时间：
2002-04-01
影响因子：
1.9
通讯作者：
Lööf, L
中科院分区：
文献类型：
--
作者：
Nordin, K;Påhlman, L;Lööf, L
背景：炎症性肠病（IBD）的慢性性以及药物和手术治疗的影响可能会影响患者的日常生活，从而损害他们与健康相关的生活质量和心理健康。方法：对瑞典 IBD 患者的人群样本进行了与健康相关的生活质量和心理困扰的调查。共有 492 名患者填写了简表 36 (SF-36)、炎症性肠病问卷 (IBDQ) 和医院焦虑和抑郁 (HAD) 量表，其中 331 名患有溃疡性结肠炎 (UC)，161 名患有克罗恩病 (CD)。结果：UC 患者在健康相关和疾病特异性生活质量的各个方面均比 CD 患者表现出更高（更好）的水平。结论：回肠造口术似乎不会影响患者的生活质量，而回肠肛门吻合术似乎在多个评估维度上降低了患者的生活质量。 CD 患者比 UC 患者报告更多的焦虑和抑郁。克罗恩病组中较高的心理困扰可以用更严重的疾病症状来解释。回肠肛门吻合术可能会导致更多的焦虑和抑郁，而回肠造口术则不会。
Background: The chronicity of inflammatory bowel disease (IBD) and effects of medical and surgical treatments probably affect the daily lives of patients and may thus impair their health-related quality of life and psychological well-being. Methods: Health-related quality of life and psychological distress were investigated in a population-based Swedish sample of patients with IBD. A total of 492 patients, 331 with ulcerative colitis (UC) and 161 with Crohn disease (CD), filled out the Short Form-36 (SF-36), the Inflammatory Bowel Disease Questionnaire (IBDQ) and the Hospital Anxiety and Depression (HAD) scale. Results: Patients with UC reported higher (superior) levels in all dimensions of health-related and disease-specific quality of life than did patients with CD. Conclusions: Having an ileostomy does not seem to affect patients' quality of life, while having ileoanal anastomosis appears to reduce patients' quality of life in several of the dimensions assessed. CD patients reported more anxiety and depression than did patients with UC. The higher psychological distress in the CD group could be explained by more severe symptoms of the disease. Having ileoanal anastomosis may lead to more anxiety and depression, while having an ileostomy does not.